Association between the use of magnesium sulfate as neuroprotector in prematurity and the neonatal hemodynamic effects

dc.contributor.authorNunes, Rodrigo Dias
dc.contributor.authorSchutz, Flávia Duarte
dc.contributor.authorTraebert, Jefferson
dc.coverage.spatialChicagopt_BR
dc.date.accessioned2017-07-27T16:54:52Z
dc.date.accessioned2020-11-26T17:34:35Z
dc.date.available2017-07-27T16:54:52Z
dc.date.available2020-11-26T17:34:35Z
dc.date.issued2017
dc.description.abstractPurpose: Cerebral palsy is often associated with prematurity and magnesium sulfate (MgSO4) has been used as a neuroprotector, with favorable results. However, its mechanism of action has not been fully elucidated. This study aimed to evaluate the association between MgSO4 at the imminent premature delivery and neonatal hemodynamic effects. Materials and methods: A cross-sectional study involving 94 newborns (NB) between 24 and 32weeks at a Brazilian hospital was performed. Bivariate analysis between the use or the non- use of MgSO4 and hemodynamic characteristics was performed, using the Chi-square test. Results: NB were evaluated between those who received MgSO4 (27.7) and those who did not (72.3%). Normal heart rate was verified in 62.8% of NB, normal respiratory rate in 70.2%, and nor- mal temperature in 22.3%. Oxygen saturation higher or equal than 95% was evidenced in 85.1% of NB, normal hemoglucotest in 74.5%, and hemoglobin greater or equal than 16.4g/dL in 30.9%. Non-invasive ventilation was performed in 48.9% of NB, while 51.1% were submitted to endotracheal ventilation. There was no significance relation detected between the use of MgSO4 and the hemodynamic characteristics. Conclusions: MgSO4 does not appear to influence hemodynamic factors as a cause of the neu- roprotection in premature NB.pt_BR
dc.format.extentp.1-6pt_BR
dc.identifier.issn1476-7058pt_BR
dc.identifier.urihttp://www.tandfonline.com/doi/full/10.1080/14767058.2017.1332033pt_BR
dc.identifier.urihttps://repositorio.animaeducacao.com.br/handle/ANIMA/2623
dc.language.isoen_USpt_BR
dc.relation.ispartofseries2pt_BR
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Brazil*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/br/*
dc.subjectMagnesium sulfatept_BR
dc.subjectHemodynamicspt_BR
dc.subjectInfantpt_BR
dc.subjectPrematurept_BR
dc.subjectNeuroprotectionpt_BR
dc.subjectFetal outcomept_BR
dc.titleAssociation between the use of magnesium sulfate as neuroprotector in prematurity and the neonatal hemodynamic effectspt_BR
dc.typeArtigo de Periodicopt_BR
local.affiliation.iesUnisul
local.author.cursoProdução Científicapt_BR
local.author.unidadeÂnimapt_BR
local.subject.areaCiências da Saúdept_BR
local.subject.areaanimaCiências Humanaspt_BR

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