Uso da Cannabis sativa no tratamento da epilepsia
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Data
2023-12
Tipo de documento
Monografia
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Modalidade de acesso
Acesso aberto
Editora
Autores
BATISTA, Gabriela Aiala Gonzaga
GOMES, Raíssa Bárbara
FERREIRA, Stéphane Silva
PAIXÃO, Nikolas Alves Lima
SANTOS, Alexandre Alves Maia
SANTOS, Mirian Tamara Fernandes dos
SILVEIRA, Gabriel Salomão
SOUSA, Ana Luiza da Silva
VENTURA, Simone de Souza
Orientador
CAROBIN, Natália Virtude
Coorientador
Resumo
A epilepsia é uma doença neurológica onde as células do cérebro trabalham em conjunto e se comunicam através de sinais elétricos, gerando uma hiperatividade neuronal e alteração nos circuitos cerebrais, podendo levar a descargas elétricas excessivas e sincrônicas. O presente estudo tem como objetivo apresentar as propriedades benéficas do canabidiol (CBD) e efeitos adversos no tratamento da epilepsia refratária. A elaboração desta revisão foi feita a partir de busca e seleção. Sendo realizadas buscas nas bases de dados: Google Acadêmico, PubMed, Scielo e Ministério da Saúde, além de livros físicos como também de bibliotecas virtuais, publicados no período de 2003 a 2023. O uso do CBD, no tratamento para epilepsia, de acordo com uma revisão bibliográfica realizada neste trabalho, tem se mostrado eficaz, influenciando positivamente no estilo de vida do paciente, apesar de manifestar alguns efeitos adversos no tratamento. No entanto, quanto à legislação, os entraves burocráticos e inconsistência nas leis dificultam a regulamentação do plantio e manipulação da Cannabis para seu efetivo uso medicinal.
The epilepsy is a neurological disease, where brain cells work together and communicate through electrical signals, generating neuronal hyperactivity and in change brains circuits, which can lead to electrical and excessive and synchronouos discharges. The presente study aims to presente the beneficial properties of cannabidiol (CBD) and adverse effects in treatment of refractory epilepsy. The preparation of this review it was made from research and selection. The searchs where carried out in databases: Academic Google, PubMed, Scielo and the Ministry of health, besides books, as well as virtual libraries, published in the period of 2003 to 2023. The use of CDB, in treatment to epilepsy, acoording to a bibliographical review, carried ou in this work, has shown itself effective, positively influencing the patient’s lifestyle, despite manifest some adverse effects during treatment. However, regarding legislation, the bureaucratic obstacles and the inconsustency in laws make it difficult the regulation of planting and manipulation from Cannabis for its effective medicinal use.
The epilepsy is a neurological disease, where brain cells work together and communicate through electrical signals, generating neuronal hyperactivity and in change brains circuits, which can lead to electrical and excessive and synchronouos discharges. The presente study aims to presente the beneficial properties of cannabidiol (CBD) and adverse effects in treatment of refractory epilepsy. The preparation of this review it was made from research and selection. The searchs where carried out in databases: Academic Google, PubMed, Scielo and the Ministry of health, besides books, as well as virtual libraries, published in the period of 2003 to 2023. The use of CDB, in treatment to epilepsy, acoording to a bibliographical review, carried ou in this work, has shown itself effective, positively influencing the patient’s lifestyle, despite manifest some adverse effects during treatment. However, regarding legislation, the bureaucratic obstacles and the inconsustency in laws make it difficult the regulation of planting and manipulation from Cannabis for its effective medicinal use.
Palavras-chave
Cannabis Sativa, canabidiol, epilepsia, epilepsia refratária