Mastocitoma de alto grau em canino: relato de caso
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Data
2023-11
Tipo de documento
Artigo Científico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências Agrárias
Modalidade de acesso
Acesso aberto
Editora
Autores
SANTOS, Talita Yasmin Hilário dos
TAMANINI, Andreia Neves de Oliveira
URBAINSKI, Maria Filomena da Silva
CRISTOFOLINI, Carolina
Orientador
OLIVEIRA, Eduardo Alexandre de
Coorientador
Resumo
O mastocitoma é uma neoplasia maligna com origem nos mastócitos, células essas participantes do sistema imunitário. É um tumor comum em cães e possui capacidade de afetar diversos órgãos e tecidos, como em cavidade oral, nasofaringe e trato gastrointestinal, porém tem apresentação mais comumente cutânea. Na literatura é descrito como maior ocorrência em cães sem raça definida (SRD), Boxer, Boston Terrier, Beagle, Bulldog, Sharpei, entre outras raças. Não possui predisposição sexual, porém é mais comumente visto em animais mais idosos, com idades por volta de oito a nove anos. Sua etiologia ainda é incerta, em alguns estudos sugerem que esse tumor possui envolvimento de inflamações crônicas, carcinógenos tópicos, predisposição hereditária e por infecções virais. Seu diagnóstico é por meio de citologia e histopatológico. O tratamento depende da graduação avaliada por meio do histopatológico, tendo técnicas de ressecção cirúrgicas, quimioterapia e eletroquimioterapia. O prognóstico é bem variável, e dependerá da graduação do tumor e estadiamento do paciente. Objetivou-se com o presente trabalho, relatar o caso de um canino, fêmea, castrada, sem raça definida, possuindo 13 anos de idade, apresentando um tumor ulcerativo com evolução de 4 meses, diagnosticada com mastocitoma grau II (alto grau), da qual realizou ressecção cirúrgica e quimioterapia antineoplásica, em decorrência a agressividade do tumor e tratamento, houve piora no quadro clínico geral da paciente, sendo assim realizado a eutanasia da mesma.
Mastocytoma is a malignant neoplasm originating from mast cells, these immune system participants. It is a common tumor in dogs and has the ability to affect various organs and tissues, such as in the oral cavity, nasopharynx and gastrointestinal tract, but has more commonly cutaneous presentation. In the literature it is described as the highest occurrence of dogs without defined breed (SRD), Boxer, Boston Terrier, Beagle, Bulldog, Sharpei, among other breeds. It has no sexual predisposition, but is most commonly seen in older animals, aged around eight to nine years. Its etiology is still uncertain, in some studies suggest that this tumor has involvement of chronic inflammation, topical carcinogens, hereditary predisposition and viral infections. Its diagnosis is through cytology and histopathology. The treatment depends on the grading evaluated through histopathological, having surgical resection techniques, chemotherapy and electrochemotherapy. The prognosis is quite variable, and will depend on the tumor graduation and staging of the patient. The objective of this study was to report the case of a canine, female, castrated, without defined breed, having 13 years of age, presenting a ulcerative tumor with evolution of 4 months, diagnosed with Mastocitoma grade II (high degree) of which performed surgical resection and antineoplastic chemotherapy, due to the aggressiveness of the tumor and treatment, there was worsening in the general clinical picture of the patient, and thus performed the euthanasia of the same.
Mastocytoma is a malignant neoplasm originating from mast cells, these immune system participants. It is a common tumor in dogs and has the ability to affect various organs and tissues, such as in the oral cavity, nasopharynx and gastrointestinal tract, but has more commonly cutaneous presentation. In the literature it is described as the highest occurrence of dogs without defined breed (SRD), Boxer, Boston Terrier, Beagle, Bulldog, Sharpei, among other breeds. It has no sexual predisposition, but is most commonly seen in older animals, aged around eight to nine years. Its etiology is still uncertain, in some studies suggest that this tumor has involvement of chronic inflammation, topical carcinogens, hereditary predisposition and viral infections. Its diagnosis is through cytology and histopathology. The treatment depends on the grading evaluated through histopathological, having surgical resection techniques, chemotherapy and electrochemotherapy. The prognosis is quite variable, and will depend on the tumor graduation and staging of the patient. The objective of this study was to report the case of a canine, female, castrated, without defined breed, having 13 years of age, presenting a ulcerative tumor with evolution of 4 months, diagnosed with Mastocitoma grade II (high degree) of which performed surgical resection and antineoplastic chemotherapy, due to the aggressiveness of the tumor and treatment, there was worsening in the general clinical picture of the patient, and thus performed the euthanasia of the same.
Palavras-chave
neoplasia, oncologia, tumor cutâneo, quimioterapia, cirurgia, veterinária