A anemia falciforme na população negra do Brasil: uma relação entre etnia e saúde
Nenhuma Miniatura disponível
Data
2023-12
Tipo de documento
Artigo Científico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso fechado
Editora
Autores
RIBEIRO, Ana Cecília de Castro
PINTO, Mariana Pereira Andrade
Orientador
ASSIS, Danielle Nogueira de
Coorientador
AMARAL, Clara Araújo Veloso
Resumo
A anemia falciforme é uma doença genética e hereditária causada por uma mutação genética que resulta em alteração na estrutura da hemoglobina. No Brasil, o processo de miscigenação, após a entrada de negros escravizados, proporcionou a disseminação das características genéticas dessa população no país. A característica do formato de foice da hemoglobina propicia graves sintomas clínicos, como vasoclusão, resultando em isquemia tecidual, desencadeando crises dolorosas, além de levar a possível insuficiência de alguns órgãos. O objetivo do estudo é reunir e analisar as evidências científicas disponíveis, relacionadas à anemia falciforme em negros no Brasil. Trata-se de uma revisão integrativa de literatura a partir de buscas ativas nas bases de dados Scielo, MEDLINE via plataforma PubMed e Biblioteca Virtual de Saúde (BVS) e LILACS também via BVS. Foram incluídos artigos obtidos na íntegra e acesso livre, nas línguas portuguesa e inglesa e publicados nos últimos 20 anos. Excluídos aqueles cujo título e resumo não estavam dentro do tema e os duplicados. Ao total foram encontrados 1930 artigos. Após aplicação dos critérios de inclusão e exclusão totalizaram 18 artigos e, após leitura na íntegra, selecionados 11 artigos, acrescentado um manual do Ministério da Saúde. A disparidade que afeta os pacientes de origem negra, tanto ao nível de doenças individuais quanto em seu contexto global torna o enfrentamento à anemia falciforme um problema de saúde pública que requer políticas públicas de saúde estruturadas e melhor assistência de informação à população negligenciada, a fim de minimizar os danos e disseminação da doença.
Sickle cell anemia is a genetic and hereditary disease characterized by a mutation in the structure of hemoglobin. In Brazil, the miscegenation process after the entry of enslaved black people led to the dissemination of genetic characteristics in the country. The characteristic sickle shape of hemoglobin leads to serious clinical symptoms, such as vasocclusion, resulting in tissue ischemia, triggering episodes of acute pain, in addition to leading to possible failure of some organs. The objective of the study is to gather and analyze the available scientific evidence related to sickle cell anemia in black people in Brazil. This is an integrative literature review based on active searches in the Scielo, MEDLINE databases via the PubMed platform and the Virtual Health Library (VHL) and LILACS also via the VHL. Articles obtained in full and free access, in Portuguese and English and published in the last 20 years, were included. Those that did not meet the inclusion criteria, those whose title and abstract were not within the topic and those that were duplicates were excluded. In total, 1930 articles were found, after applying the inclusion and exclusion criteria, 18 articles totaled and after reading in full, 11 articles were selected, adding a manual from the Ministry of Health. The disparity that affects patients of black origin, both in terms of individual diseases and in its global context makes tackling sickle cell anemia a public health problem that requires structured public health policies and better information assistance to the neglected population in order to minimize the damage and spread of the disease.
Sickle cell anemia is a genetic and hereditary disease characterized by a mutation in the structure of hemoglobin. In Brazil, the miscegenation process after the entry of enslaved black people led to the dissemination of genetic characteristics in the country. The characteristic sickle shape of hemoglobin leads to serious clinical symptoms, such as vasocclusion, resulting in tissue ischemia, triggering episodes of acute pain, in addition to leading to possible failure of some organs. The objective of the study is to gather and analyze the available scientific evidence related to sickle cell anemia in black people in Brazil. This is an integrative literature review based on active searches in the Scielo, MEDLINE databases via the PubMed platform and the Virtual Health Library (VHL) and LILACS also via the VHL. Articles obtained in full and free access, in Portuguese and English and published in the last 20 years, were included. Those that did not meet the inclusion criteria, those whose title and abstract were not within the topic and those that were duplicates were excluded. In total, 1930 articles were found, after applying the inclusion and exclusion criteria, 18 articles totaled and after reading in full, 11 articles were selected, adding a manual from the Ministry of Health. The disparity that affects patients of black origin, both in terms of individual diseases and in its global context makes tackling sickle cell anemia a public health problem that requires structured public health policies and better information assistance to the neglected population in order to minimize the damage and spread of the disease.
Palavras-chave
anemia falciforme, negros, saúde