Associação entre o vírus da Herpes Simplex tipo 2 e o HIV
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Data
2023-12
Tipo de documento
Artigo Científico
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Área do conhecimento
Modalidade de acesso
Acesso aberto
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Autores
MENNA, Danielly Cavalheiro
Orientador
QUATRIN, Priscilla Maciel
Coorientador
Resumo
O vírus HIV (Vírus da Imunodeficiência Humana) é o causador da AIDS (Síndrome da Imunodeficiência humana adquirida), sendo o responsável por causar comprometimento ao sistema imunológico do indivíduo contaminado. A transmissão pode ocorrer através de relações sexuais desprotegidas (vaginal, anal ou oral), todavia, o uso de objetos perfuro cortantes que estejam contaminados como, por exemplo, alicates, agulhas, escalpes, podem transmitir a doença. Através de pesquisas em pacientes portadores do vírus HIV, foi então descoberto que os mesmos possuem maior prevalência de serem contaminados também com Herpes Genital Simplex tipo 2, devido ao maior comprometimento do sistema imunológico. Em pacientes imunodeprimidos, os sintomas ocorrem normalmente entre 2 a 3 semanas, mas podemos observar que, quando portadores de HIV, os sintomas se prolongam por períodos superiores a 30 dias, mesmo que, com tratamentos a base de antivirais. A importância da correlação entre exames físicos e laboratoriais é extremamente necessária para proporcionar intervenções terapêuticas ao paciente acometido, uma vez que, a contaminação por estes dois vírus, pode levar ao óbito. O objetivo deste artigo busca avaliar o comprometimento do sistema imunológico de pacientes infectados pelos vírus, avaliar os mecanismos responsáveis pelo aumento da incidência de HIV em pacientes com Herpes tipo 2 e identificar as formas de prevenção sobre os respectivos vírus.
The HIV virus (Human Immunodeficiency Virus) is the cause of AIDS (Acquired Human Immunodeficiency Syndrome), being responsible for compromising the immune system of the infected individual. Transmission can occur through unprotected sexual intercourse (vaginal, anal or oral), however, the use of sharp objects that are contaminated, such as pliers, needlesik, can transmit the disease. Through research on patients with the HIV virus, it was discovered that they also have a higher prevalence of being infected with Genital Herpes Simplex type 2, due to the greater impairment of the immune system. In immunocompromised patients, symptoms normally occur for 2 to 3 weeks, but we can observe that, when carrying HIV, symptoms last for periods longer than 30 days, even with antiviral-based treatments. The importance of the correlation between physical and laboratory examinations is extremely necessary to provide therapeutic interventions to the affected patient, since contamination by these two viruses can lead to death. The objective of this article seeks to evaluate the impairment of the immune system of patients infected by viruses, evaluate the mechanisms responsible for the increase in the incidence of HIV in patients with Herpes type 2 and identify forms of prevention against the respective viruses.
The HIV virus (Human Immunodeficiency Virus) is the cause of AIDS (Acquired Human Immunodeficiency Syndrome), being responsible for compromising the immune system of the infected individual. Transmission can occur through unprotected sexual intercourse (vaginal, anal or oral), however, the use of sharp objects that are contaminated, such as pliers, needlesik, can transmit the disease. Through research on patients with the HIV virus, it was discovered that they also have a higher prevalence of being infected with Genital Herpes Simplex type 2, due to the greater impairment of the immune system. In immunocompromised patients, symptoms normally occur for 2 to 3 weeks, but we can observe that, when carrying HIV, symptoms last for periods longer than 30 days, even with antiviral-based treatments. The importance of the correlation between physical and laboratory examinations is extremely necessary to provide therapeutic interventions to the affected patient, since contamination by these two viruses can lead to death. The objective of this article seeks to evaluate the impairment of the immune system of patients infected by viruses, evaluate the mechanisms responsible for the increase in the incidence of HIV in patients with Herpes type 2 and identify forms of prevention against the respective viruses.
Palavras-chave
HIV, AIDS, HSV-2, IST, TDF, TFV, IVRs