Cannabis sativa na medicina veterinária: revisão de literatura
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Data
2023-11
Tipo de documento
Artigo Científico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Modalidade de acesso
Acesso aberto
Editora
Autores
SILVA, Bruna Rocha
XAVIER, Naiara Almeida
ALMEIDA, Nathália Vitrio de
Orientador
SCHEIBEL, Suellen
Coorientador
Resumo
A Cannabis sativa Linnaeus é uma planta que contém mais de 400 substâncias químicas, 60 delas se classificam como canabinoides. O canabidiol (CBD) é uma substância que não causa efeitos psicoativas ou dependência, esse elemento possui uma estrutura química com grande potencial terapêutico, incluindo a capacidade de tratar a dor neuropática, inflamatória e a osteoartrose. No cérebro, os receptores canabinóides tipo 1 presentes podem modular a dor através da liberação de neurotransmissores que previnem a hiperatividade neuronal e promovem uma leve sedação e redução da ansiedade. Já receptores canabinóides tipo 2, o THC, tem ótimo desempenho contra a inflamação, mostrando ter grandes benefícios anti-inflamatórios e analgésicos. Na prática veterinária, é comum o uso de medicamentos aplicados em seres humanos utilizados em animais. No entanto, no cenário atual, o uso de produtos derivados da Cannabis para fins terapêuticos é permitido somente em seres humanos, com prescrição exclusiva de médicos autorizados pelo Conselho Federal de Medicina. Esta revisão tem como objetivo unificar os mais diversos estudos, destacando desde o histórico da planta, o funcionamento no organismo, os benefícios e efeitos colaterais, a partir de evidências científicas, referentes ao efeito do cannabidiol (CBD), pois ainda se faz necessária muita cautela e pesquisas acerca de seu uso, devido a sua diversidade química e processos biomoleculares desencadeados no organismo dos animais.
Cannabis sativa Linnaeus is a plant that contains more than 400 chemical substances, 60 of which are classified as cannabinoids. Cannabidiol (CBD) is a substance that does not cause psychoactive or addictive effects. This element has a chemical structure with great therapeutic potential, including the ability to treat neuropathic and inflammatory pain and osteoarthritis. In the brain, the type 1 cannabinoid receptors present can modulate pain through the release of neurotransmitters that prevent neuronal hyperactivity and promote mild sedation and reduced anxiety. Type 2 cannabinoid receptors, THC, have excellent performance against inflammation, showing great anti-inflammatory and analgesic benefits. In veterinary practice, it is common to use medicines applied to humans and used in animals. However, in the current scenario, the use of products derived from Cannabis for therapeutic purposes is only permitted in humans, with exclusive prescription from doctors authorized by the Federal Council of Medicine. This review aims to unify the most diverse studies, highlighting everything from the history of the plant, its functioning in the body, the benefits and side effects, based on scientific evidence, referring to the effect of cannabidiol (CBD), as much caution and research into its use, due to its chemical diversity and biomolecular processes triggered in the animals' bodies.
Cannabis sativa Linnaeus is a plant that contains more than 400 chemical substances, 60 of which are classified as cannabinoids. Cannabidiol (CBD) is a substance that does not cause psychoactive or addictive effects. This element has a chemical structure with great therapeutic potential, including the ability to treat neuropathic and inflammatory pain and osteoarthritis. In the brain, the type 1 cannabinoid receptors present can modulate pain through the release of neurotransmitters that prevent neuronal hyperactivity and promote mild sedation and reduced anxiety. Type 2 cannabinoid receptors, THC, have excellent performance against inflammation, showing great anti-inflammatory and analgesic benefits. In veterinary practice, it is common to use medicines applied to humans and used in animals. However, in the current scenario, the use of products derived from Cannabis for therapeutic purposes is only permitted in humans, with exclusive prescription from doctors authorized by the Federal Council of Medicine. This review aims to unify the most diverse studies, highlighting everything from the history of the plant, its functioning in the body, the benefits and side effects, based on scientific evidence, referring to the effect of cannabidiol (CBD), as much caution and research into its use, due to its chemical diversity and biomolecular processes triggered in the animals' bodies.
Palavras-chave
Animais, Canabidiol, Receptores, Terapêutico