Aspectos Clínicos da Ceratite fúngica: uma revisão de literatura
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Data
2022-12-12
Tipo de documento
Artigo Científico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso aberto
Editora
Autores
Casado, Larissa da Silva
Gomes, Regilberto da Silva
Orientador
Souza, Fabia Julliana Jorge de
Coorientador
Resumo
A ceratite fúngica é uma condição clínica que quando não tratada pode levar à
endoftalmite e a destruição da córnea, com perda de visão. A doença foi
documentada primeira vez em 1879 sua incidência vem aumentando nos últimos 30
anos. Dessa forma, o objetivo do presente estudo foi investigar origens, caraterísticas
clínicas, ocorrência e a incidência, distribuição geográfica da ceratite fúngica e as
relações existentes entre todos os fatores que desencadeiam e potencializam esta
condição clínica. A metodologia utilizada foi uma revisão de literatura integrativa,
foram incluídas publicações em línguas portuguesa e inglesa, com tema ou com
assuntos relacionados ao tema, foram excluídos materiais incompletos, que
abordassem o tema em outros conteúdos específicos que divergiam do objetivo
deste trabalho. Atualmente, sabe-se que de 100 espécies diferentes de fungos são
capazes de causar ceratite fúngica. Em relação ao gênero responsável pela ceratite
fúngica, depende de vários fatores, incluindo fatores de risco pessoais, temperatura
regional, condições climáticas, geografia e urbanização. O diagnóstico e o manejo
precoce, são essenciais para prevenir complicações a longo prazo, incluindo
cegueira e perda do globo ocular. Além disso, fatores como trauma, estado
imunocomprometido, doença da superfície ocular e uso de lentes de contato são os
fatores de risco pessoais mais prevalentes associados à ceratite fúngica e podem
predispor diferentes tipos de infecções fúngicas. Dessa forma, como base na revisão
da literatura realizada concluímos que clinicamente pode ser um desafio diagnosticar
a ceratite fúngica. Além disso, foram observadas limitações quanto aos tratamentos
disponíveis, e atrasos no diagnóstico com resultados cultura negativos ou tardios.
Fungal keratitis is a clinical condition that when left untreated can lead to endophthalmitis and corneal destruction, with loss of vision. The disease was first documented in 1879 and its incidence has been increasing over the last 30 years. Thus, the puppose of this study is to investigate the origins, clinical characteristics, occurrence, incidence and geographical distribution of fungal keratitis and the factors that trigger and enhance this clinical condition. The methodology used was an integrative literature review; publications in Portuguese and English included, with the theme or with subjects related; incomplete materials that approached the theme in other specific contents that diverged from the purppose of this work were excluded. Currently, it is known that over 100 different species of fungal are capable of causing fungal keratitis. The specific type of fungus responsible for fungal keratitis depends on several factors, including personal risk factors, regional temperature, climatic conditions, geography and urbanization. Early diagnosis and management are therefore essential to prevent long-term complications, including blindness and loss of the eyeball. In addition, factors such as trauma, immunocompromised status, ocular surface disease and contact lens use are the most prevalent personal risk factors associated with fungal keratitis and may predispose to different types of fungal infections. Thus, based on this review we assume that clinically it can be challenging to diagnose a fungal infection as the cause of keratitis and delays in diagnosis are frequent with negative or delayed fungal growth results.
Fungal keratitis is a clinical condition that when left untreated can lead to endophthalmitis and corneal destruction, with loss of vision. The disease was first documented in 1879 and its incidence has been increasing over the last 30 years. Thus, the puppose of this study is to investigate the origins, clinical characteristics, occurrence, incidence and geographical distribution of fungal keratitis and the factors that trigger and enhance this clinical condition. The methodology used was an integrative literature review; publications in Portuguese and English included, with the theme or with subjects related; incomplete materials that approached the theme in other specific contents that diverged from the purppose of this work were excluded. Currently, it is known that over 100 different species of fungal are capable of causing fungal keratitis. The specific type of fungus responsible for fungal keratitis depends on several factors, including personal risk factors, regional temperature, climatic conditions, geography and urbanization. Early diagnosis and management are therefore essential to prevent long-term complications, including blindness and loss of the eyeball. In addition, factors such as trauma, immunocompromised status, ocular surface disease and contact lens use are the most prevalent personal risk factors associated with fungal keratitis and may predispose to different types of fungal infections. Thus, based on this review we assume that clinically it can be challenging to diagnose a fungal infection as the cause of keratitis and delays in diagnosis are frequent with negative or delayed fungal growth results.
Palavras-chave
ceratite microbiana, fungos, ceratomiose