Efeitos do CPAP nos desfechos cardiorrespiratórios em pacientes com apneia obstrutiva do sono e insuficiência cardíaca: uma revisão sistemática
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Data
2022-12-15
Tipo de documento
Artigo Científico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso fechado
Editora
Autores
Martins, Marcia da Silva
Orientador
Araujo, Francisco Xavier de
Coorientador
Resumo
A apneia obstrutiva do sono é um problema de saúde pública de grande
impacto econômico. Estima-se que a prevalência de portadores de AOS fica entre 4% a 6% dos homens e 2% a 4% das mulheres da população em geral, com incidência aumentada na faixa etária acima dos 70 anos, Dados epidemiológicos mostram que em muitos casos a apneia obstrutiva do sono não é diagnosticada. Há fortes evidências que ambos os distúrbios do sono e a Insuficiência Cardíaca estão relacionadas o que pode provocar elevado aumento de morbidade cardiovascular, a pressão positiva contínua nas vias aéreas (CPAP) é o tratamento não farmacólogico padrão ouro para essa população. No entando ainda há uma lacuna na literatura e não está totalmente claro seus efeitos em pacientes com AOS e IC. Objetivo: Avaliar através de ensaios clínicos randomizados os efeitos da pressão positiva na função
cardiorrespiratória em pacientes com AOS e IC.
Introduction: Obstructive sleep apnea is a public health problem with a great economic impact.It is estimated that the prevalence of OSA carriers is between 4% to 6% of men and 2% to 4% of women in the general population, with an increased incidence in the age group above 70 years. Epidemiological data show that in many cases Obstructive sleep apnea is not diagnosed. There is strong evidence that both sleep disorders and heart failure are related, which can cause a high increase in cardiovascular morbidity, continuous positive airway pressure (CPAP) is the gold standard non-pharmacological treatment for this population. However, there is still a gap in the literature and its effects in patients with OSA and HF are not entirely clear. Objective: To evaluate, through randomized clinical trials, the effects of positive pressure on cardiorespiratory function in patients with OSA and HF, Methods: Randomized clinical trials were included, with publication in the MEDLINE, PEDro, Cochrane Library, Scielo and PubMed databases and the risk bias was assessed using the PEDro scale.Results: Six articles were included in this study, totaling 165 participants. Our findings demonstrate that CPAP in the treatment of obstructive sleep apnea in patients with heart failure promotes an increase in left ventricular ejection fraction, oxygen saturation and a reduction in blood pressure, in apnea/hypopnea indices and in awakenings. sleep at night. Conclusion: Our systematic review demonstrates that CPAP treatment improves cardiorespiratory outcomes in patients with OSA and HF, improving prognosis and reducing the risk of sudden death. However, their data must be interpreted with caution considering the bias of the studies and their limitations.
Introduction: Obstructive sleep apnea is a public health problem with a great economic impact.It is estimated that the prevalence of OSA carriers is between 4% to 6% of men and 2% to 4% of women in the general population, with an increased incidence in the age group above 70 years. Epidemiological data show that in many cases Obstructive sleep apnea is not diagnosed. There is strong evidence that both sleep disorders and heart failure are related, which can cause a high increase in cardiovascular morbidity, continuous positive airway pressure (CPAP) is the gold standard non-pharmacological treatment for this population. However, there is still a gap in the literature and its effects in patients with OSA and HF are not entirely clear. Objective: To evaluate, through randomized clinical trials, the effects of positive pressure on cardiorespiratory function in patients with OSA and HF, Methods: Randomized clinical trials were included, with publication in the MEDLINE, PEDro, Cochrane Library, Scielo and PubMed databases and the risk bias was assessed using the PEDro scale.Results: Six articles were included in this study, totaling 165 participants. Our findings demonstrate that CPAP in the treatment of obstructive sleep apnea in patients with heart failure promotes an increase in left ventricular ejection fraction, oxygen saturation and a reduction in blood pressure, in apnea/hypopnea indices and in awakenings. sleep at night. Conclusion: Our systematic review demonstrates that CPAP treatment improves cardiorespiratory outcomes in patients with OSA and HF, improving prognosis and reducing the risk of sudden death. However, their data must be interpreted with caution considering the bias of the studies and their limitations.
Palavras-chave
Pressão Positiva Contínua nas vias Aéreas, Apneia Obstrutiva do Sono, Insuficiência Cardíaca