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Artigo de Periodico Acesso aberto Incidência de sepse nosocomial em adultos de uma unidade de terapia intensiva, Tubarão (SC), em 2013(2017) Anselmo Júnior, Emídio; Dall'Stella, Daniel Kolczycki; Araújo, Jane Martins de; Souza, Everson da Silva; Schuelter-Trevisol, FabianaOBJECTIVE: Sepsis is a highly prevalent syndrome in intensive care units, associated with a high mortality rate with late diagnosis. The objective of this study was to determine the incidence and epidemiological profile of nosocomial sepsis, associated risk factors and the source of the infection that could aid in the creation or inclusion of preventable measures METHODS: Retrospective cohort design. The infection notification sheets available from the Hospital Infection Control Commission were supplemented with data from the electronic records of patients admitted to the intensive care unit in the year 2013. RESULTS: There were 1,345 patients admitted to the ICU in the year 2013 and 130 cases of sepsis among 96 patients, resulting in an incidence rate of 9.7%. The majority of cases occurred among men (67.7%) and the mean age was 62 ± 16.4 years. The length of hospital stay had a median of 36.5 days. The most common source of infection was the respiratory tract (56.2%), followed by the urinary tract (17.7%). Of the total, 44.3% patients died. CONCLUSION: The study had a low incidence of nosocomial sepsis, however, the cases had a high hospital stay with a high mortality rate.Artigo de Periodico Acesso aberto New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infecions: report of a survivor(2016) Schuelter-Trevisol, Fabiana; Schmitt, Graciane Jacinta; Araújo, Jane Martins de; Souza, Liliane Braga de; Nazário, Juliana Gomes; Januário, Raquel Landuchi; Mello, Rogério Sobroza; Trevisol, Daisson JoséNew Delhi metallo-beta-lactamase-1 (NDM-1) is a bacterial enzyme that renders the bacteria resistant to a variety of beta-lactam antibiotics. A 20-year-old man was hospitalized several times for surgical treatment and complications caused by a right-sided vestibular schwannoma. Although the patient acquired several multidrug-resistant infections, this study focuses on the NDM- 1-producing Acinetobacter spp. infection. As it was resistant to all antimicrobials tested, the medical team developed a 20-day regimen of 750mg/day metronidazole, 2,000,000IU/day polymyxin B, and 100mg/day tigecycline. The treatment was effective, and the patient recovered and was discharged from the hospital.