Os efeitos da aplicação de bioestimuladores de colágeno no envelhecimento facial
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Data
2021-11
Tipo de documento
Artigo Científico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso fechado
Editora
Autores
Miranda, Daiany
Mayumi Gimenes de Barros, Odhara
Orientador
Cascaes, Franciele
Coorientador
Resumo
A procura por intervenções estéticas vêm aumentando significativamente, principalmente no que diz respeito a procedimentos faciais menos invasivos, que promovem a melhora da aparência e saúde da pele. Os bioestimuladores de colágeno
estimulam a produção de colágeno local, através da ativação de fibroblastos para produção de novas fibras de colágeno e preenchimento de volume. O objetivo desta revisão foi descrever sobre os efeitos da aplicação dos bioestimuladores de colágeno no envelhecimento facial, assim como apresentar as características físico-químicas dos bioestimuladores, suas indicações, contraindicações e mecanismo de ação. Foram consultadas as bases de dados científicas Pubmed, Scielo e Google Acadêmico no período de setembro a outubro de 2021 utilizando a seguinte estratégia de busca: “preenchimentos”, “preenchimento dérmico”, “bioestimuladores”, “envelhecimento facial”, “colágeno”, “hidroxiapatita de cálcio”, “ácido poli-l-lático”,
“Sculptra”, “policaprolactona” e “Ellansé”. Devido a sua alta viscosidade e elasticidade, a Hidroxiapatita de cálcio apresenta maior estabilidade pois não se desloca facilmente para outros locais após a aplicação, e possui durabilidade média de 12 a 18 meses. Os efeitos provocados pelo Ácido poli-l-lático ocorrem de forma lenta e gradual, sendo
indicado para pacientes que desejam um resultado natural e sua durabilidade pode variar de 8 a 24 meses. Outra importante substância é a Policaprolactona, que é apresentada em 4 versões no mercado, que variam conforme a duração dos efeitos (1 a 4 anos) e a necessidade de cada paciente. A respeito dos efeitos e benefícios dos bioestimuladores até o presente momento, a Policaprolactona é o bioestimulador que apresenta os melhores resultados diante dos estudos apresentados, porém vale ressaltar a necessidade de estudos mais recentes para uma melhor comparação entre os bioestimuladores.
The search for aesthetic interventions has increased significantly, especially with regard to less invasive facial procedures, which improve the appearance and health of the skin. Collagen biostimulators stimulate local collagen production through the activation of fibroblasts to produce new collagen fibers and fill volume. The aim of this review was to describe the effects of the application of collagen biostimulators on facial aging, as well as to present the physicochemical characteristics of biostimulators, their indications, contraindications and mechanism of action. The scientific databases Pubmed, Scielo and Google Scholar were consulted from September to October 2021 using the following search strategy: "fills", "dermal fillers", "biostimulators", "facial aging", "collagen", “calcium hydroxyapatite”, “poly-l-lactic acid”, “Sculptra”, “polycaprolactone” and “Ellansé”. Due to its high viscosity and elasticity, calcium hydroxyapatite has greater stability as it does not move easily to other locations after application, and has an average durability of 12 to 18 months. The effects caused by poly-l-lactic acid occur slowly and gradually, being indicated for patients who want a natural result and its durability can vary from 8 to 24 months. Another important substance is Polycaprolactone, which is available in 4 versions on the market, which vary according to the duration of the effects (1 to 4 years) and the needs of each patient. Regarding the effects and benefits of biostimulators to date, Polycaprolactone is the biostimulator that presents the best results in the light of the studies presented, but it is worth emphasizing the need for more recent studies for a better comparison between biostimulators.
The search for aesthetic interventions has increased significantly, especially with regard to less invasive facial procedures, which improve the appearance and health of the skin. Collagen biostimulators stimulate local collagen production through the activation of fibroblasts to produce new collagen fibers and fill volume. The aim of this review was to describe the effects of the application of collagen biostimulators on facial aging, as well as to present the physicochemical characteristics of biostimulators, their indications, contraindications and mechanism of action. The scientific databases Pubmed, Scielo and Google Scholar were consulted from September to October 2021 using the following search strategy: "fills", "dermal fillers", "biostimulators", "facial aging", "collagen", “calcium hydroxyapatite”, “poly-l-lactic acid”, “Sculptra”, “polycaprolactone” and “Ellansé”. Due to its high viscosity and elasticity, calcium hydroxyapatite has greater stability as it does not move easily to other locations after application, and has an average durability of 12 to 18 months. The effects caused by poly-l-lactic acid occur slowly and gradually, being indicated for patients who want a natural result and its durability can vary from 8 to 24 months. Another important substance is Polycaprolactone, which is available in 4 versions on the market, which vary according to the duration of the effects (1 to 4 years) and the needs of each patient. Regarding the effects and benefits of biostimulators to date, Polycaprolactone is the biostimulator that presents the best results in the light of the studies presented, but it is worth emphasizing the need for more recent studies for a better comparison between biostimulators.
Palavras-chave
Bioestimuladores de colágeno, Envelhecimento facial, Ácido Poli-l-lático, Policaprolactona, Hidroxiapatita de cálcio