New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infecions: report of a survivor
Carregando...
Arquivos
Data
2016
Tipo de documento
Artigo de Periodico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso aberto
Editora
Autores
Schuelter-Trevisol, Fabiana
Schmitt, Graciane Jacinta
Araújo, Jane Martins de
Souza, Liliane Braga de
Nazário, Juliana Gomes
Januário, Raquel Landuchi
Mello, Rogério Sobroza
Trevisol, Daisson José
Orientador
Coorientador
Resumo
New Delhi metallo-beta-lactamase-1 (NDM-1) is a bacterial enzyme that renders the bacteria resistant to a variety of beta-lactam
antibiotics. A 20-year-old man was hospitalized several times for surgical treatment and complications caused by a right-sided
vestibular schwannoma. Although the patient acquired several multidrug-resistant infections, this study focuses on the NDM-
1-producing Acinetobacter spp. infection. As it was resistant to all antimicrobials tested, the medical team developed a 20-day
regimen of 750mg/day metronidazole, 2,000,000IU/day polymyxin B, and 100mg/day tigecycline. The treatment was effective,
and the patient recovered and was discharged from the hospital.
Palavras-chave
Acinetobacter, Beta-lactam resistance, Microbial drug resistance