Characterization of the Epidemiological Profile and Survival of Children with AIDS in Santa Catarina, Brazil, 1988 - 2013
Carregando...
Data
2016
Tipo de documento
Artigo de Periodico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso aberto
Editora
Autores
Schuelter-Trevisol, Fabiana
Crocetta, Amanda Sandrini
Magajewski, Flavio Ricardo Liberali
Freitas, Paulo Fontoura
Silva, Helena Caetano Gonçalves
Trevisol, Daisson José
Orientador
Coorientador
Resumo
Background: It is estimated that survival of children with perinatally transmitted acquired immunodeficiency syndrome (AIDS)
in Brazil is around 60 months, and an upward trend has been shown over recent years. The reduction in mortality rates in Brazilian
children is mainly attributed to the effectiveness of antiretroviral therapy.
Objectives: The aim of this study was to characterize the epidemiological profile and survival rates among children diagnosed with
AIDS in the state of Santa Catarina, Brazil.
Methods: This was a retrospective cohort study of survival in children aged under 13 years who were reported to have human immunodeficiency
virus (HIV) infection in the state of Santa Catarina between 1988 and 2013. The cases were selected from the records
of HIV infection cases reported by the Information System for Notifiable and by the Mortality Information System of Santa Catarina,
Brazil.
Results: We studied 990 children whose median age at diagnosis was 26 months. Among those who died, the survival time after
diagnosis was 39.7 months on average, with a median of 16 months. Children’smeanage at death attributed to AIDS was 73.8 months,
with a median of 55 months. Of the 990 surveyed children, the median survival time was 263 months, and 14.7% died of AIDS. The
chance of survival at 60 months was estimated to be 88.1%.
Conclusions: The studied indicators suggest that the AIDS epidemic in children showed a decreasing tendency in terms of the
incidence and mortality rates with tendency, along with an unexpected growth trend in lethality rate in the last period.
Palavras-chave
Child, Acquired Immunodeficiency Syndrome, HIV, Survival Analysis