Mal de Alzheimer: associação da dieta MIND e declínio cognitivo
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Data
2023-06-27
Tipo de documento
Artigo Científico
Título da Revista
ISSN da Revista
Título de Volume
Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso fechado
Editora
Autores
Silva, Yannka Martha Santos
Orientador
Dias, Bruno Almeida
Coorientador
Resumo
A doença de Alzheimer (DA) é uma doença caracterizada pela perda progressiva e irreversível da função cognitiva que interrompe o processo de sinapse entre os neurônios. A causa está diretamente relacionada com o acúmulo do peptídeo beta-amilóide e emaranhados neurofibrilares ocasionado pela proteína tau. Estas disfunções ainda se encontram em estudo e seus sintomas podem ser atenuadas através da dietoterapia. As suas manifestações podem incluir desorientação temporal e espacial, perda de memória, bem como, problemas na linguagem e na fala. Esse artigo de revisão literária tem por objetivo apresentar dados encontrados nossites eletrônicos da PubMed e Google acadêmico, com os descritores “Nutrição e Alzheimer”, “Impacto Nutricional na doença de Alzheimer” e “Fisiopatologia do Alzheimer” para identificar o índice de eficácia da dieta Mediterrânea-DASH Intervention for Neurodegenerative Delay (MIND) diante do declínio cognitivo, comumente apresentado no Alzheimer. Atrelado a isso descreve sobre o potencial das intervenções nutricionais das dietas: Dietary Approach to Stop Hypertension (DASH) e mediterrânea, bem como, a fisiopatologia da Doença de Alzheimer e algumas considerações sobre a relação entre estilo de vida e aparecimento do Alzheimer. Este estudo encontrou uma significativa correlação entre as estratégias alimentares da dieta MIND e o declínio cognitivo, embora haja a necessidade demais estudos suficientemente convincentes.
Alzheimer's disease (AD) is a disease characterized by the progressive and irreversible loss of cognitive function that interrupts the synapse process between neurons. The cause is directly related to the accumulation of beta-amyloid peptide and neurofibrillary tangles caused by the tau protein. These dysfunctions are still under study and their symptoms can be alleviated through diet therapy. Its manifestations may include temporal and spatial disorientation, memory loss, as well as language and speech problems. This literary review article aims to present data found on the electronic sites of PubMed and Google Scholar, with the descriptors "Nutrition and Alzheimer", "Nutritional Impact on Alzheimer's Disease" and "Alzheimer's Pathophysiology" to identify the efficacy index of the Mediterranean diet-DASH Intervention for Neurodegenerative Delay (MIND) in the face of cognitive decline, commonly seen in Alzheimer's. Linked to this, he describes the potential of nutritional interventions in the Dietary Approach to Stop Hypertension (DASH) and Mediterranean diets, as well as the pathophysiology of Alzheimer's disease and some considerations about the relationship between lifestyle and the onset of Alzheimer's. This study found a significant correlation between MIND diet dietary strategies and cognitive decline, although there is a need for further sufficiently convincing studies.
Alzheimer's disease (AD) is a disease characterized by the progressive and irreversible loss of cognitive function that interrupts the synapse process between neurons. The cause is directly related to the accumulation of beta-amyloid peptide and neurofibrillary tangles caused by the tau protein. These dysfunctions are still under study and their symptoms can be alleviated through diet therapy. Its manifestations may include temporal and spatial disorientation, memory loss, as well as language and speech problems. This literary review article aims to present data found on the electronic sites of PubMed and Google Scholar, with the descriptors "Nutrition and Alzheimer", "Nutritional Impact on Alzheimer's Disease" and "Alzheimer's Pathophysiology" to identify the efficacy index of the Mediterranean diet-DASH Intervention for Neurodegenerative Delay (MIND) in the face of cognitive decline, commonly seen in Alzheimer's. Linked to this, he describes the potential of nutritional interventions in the Dietary Approach to Stop Hypertension (DASH) and Mediterranean diets, as well as the pathophysiology of Alzheimer's disease and some considerations about the relationship between lifestyle and the onset of Alzheimer's. This study found a significant correlation between MIND diet dietary strategies and cognitive decline, although there is a need for further sufficiently convincing studies.
Palavras-chave
Doença de Alzheimer (DA), Dieta Mediterrânea, Dieta DASH, Dieta MIND, Fisiopatologia do Alzheimer