Produção científica/docente
URI Permanente desta comunidade
Navegar
Navegando Produção científica/docente por Data de Publicação
Agora exibindo 1 - 20 de 169
Resultados por página
Opções de Ordenação
Artigo de Periodico Acesso aberto Turning text into research networks: information retrieval and computational ontologies in the creation of scientific Databases(2012) Ceci, Flavio; Pietrobon, Ricardo; Gonçalves, AlexandreBackground: Web-based, free-text documents on science and technology have been increasing growing on the web. However, most of these documents are not immediately processable by computers slowing down the acquisition of useful information. Computational ontologies might represent a possible solution by enabling semantically machine readable data sets. But, the process of ontology creation, instantiation and maintenance is still based on manual methodologies and thus time and cost intensive. Method: We focused on a large corpus containing information on researchers, research fields, and institutions. We ased our strategy on traditional entity recognition, social computing and correlation. We devised a semi automatic approach for the recognition, correlation and extraction of named entities and relations from textual documents which are then used to create, instantiate, and maintain an ontology. Results: We present a prototype demonstrating the applicability of the proposed strategy, along with a case study describing how direct and indirect relations can be extracted from academic and professional activities registered in a database of curriculum vitae in free-text format. We present evidence that this system can identify entities to assist in the process of knowledge extraction and representation to support ontology maintenance. We also demonstrate the extraction of relationships among ontology classes and their instances. Conclusion: We have demonstrated that our system can be used for the conversion of research information in free text format into database with a semantic structure. Future studies should test this system using the growing number of freetext information available at the institutional and national levels.Artigo de Periodico Acesso aberto Characteristics Associated to Lipodystrophy Syndrome among HIVInfected Patients Naive and on Antiretroviral Treatment(2012) Alencastro, Paulo Ricardo; Wolff, Fernando Hertz; Schuelter-Trevisol, Fabiana; Ikeda, Maria Letícia; Brandão, Ajácio Bandeira de Mello; Barcellos, Nêmora T.; Fuchs, Sandra CostaAbstract Background: HIV-associated lipodystrophy involves changes in complex metabolic networks that are associated with increased cardiovascular risk. It has been associated with the use of combined antiretroviral treatment (cART), particularly Protease Inhibitors (PI) and thymidine analogs. This study aims to evaluate characteristics and use of ART associated with lipodystrophy, lipohypertrophy, and lipoatrophy among HIV-infected patients. Methods: A cross-sectional study was conducted in HIV-infected patients of both genders, aged 18 years or older, who sought care at an HIV/AIDS referral service for diagnostic confirmation or treatment between June 2006 and December 2008. Results: 1240 out of 1295 patients with HIV infection were included. Among patients on cART, women had a higher risk of lipohypertrophy than men, as well as a time since diagnosis of HIV greater than 6 years (versus <3 years). For lipoatrophy, age, education, lifestyle, and body mass index were associated with increased risk. Metabolic parameters were higher among patients on ART; and cART and PI use were independently associated with lipohypertrophy, lipoatrophy and lipodystrophy. The use of PI can be regarded as responsible for 13% of the association of ART and lipodystrophy, and of 11.5% for the thymidine analogs use, independent of gender, skin color, smoking, CD4, and BMI. Conclusions: Risk factors for lipodystrophy, lipoatrophy and lipohypertrophy are marked among ART users, but also among ART naïve patients.Livro Acesso aberto Artigo de Periodico Acesso aberto Brazil's Family Health Strategy(2015) Trevisol, Daisson José; Traebert, Jefferson; Schuelter-Trevisol, Fabianao the Editor: The Perspective article by Macinko and Harris (June 4 issue)1 encourages us to contribute to the debate over health care in Brazil in order to clarify several key points. First, Brazil's community health agents have no specialized technical training, which prevents them from fully exercising the functions intended for them. Second, both physical facilities and human resources are inadequate, and examination quotas are insufficient to meet the demand. Health care coverage is often inefficient and provides low-quality services.2 Third, poor integration between primary care and secondary and tertiary care overloads emergency departments. Fourth, underfunding by the federal . . .Artigo de Periodico Acesso aberto New Delhi metallo-beta-lactamase-1-producing Acinetobacter spp. infecions: report of a survivor(2016) Schuelter-Trevisol, Fabiana; Schmitt, Graciane Jacinta; Araújo, Jane Martins de; Souza, Liliane Braga de; Nazário, Juliana Gomes; Januário, Raquel Landuchi; Mello, Rogério Sobroza; Trevisol, Daisson JoséNew Delhi metallo-beta-lactamase-1 (NDM-1) is a bacterial enzyme that renders the bacteria resistant to a variety of beta-lactam antibiotics. A 20-year-old man was hospitalized several times for surgical treatment and complications caused by a right-sided vestibular schwannoma. Although the patient acquired several multidrug-resistant infections, this study focuses on the NDM- 1-producing Acinetobacter spp. infection. As it was resistant to all antimicrobials tested, the medical team developed a 20-day regimen of 750mg/day metronidazole, 2,000,000IU/day polymyxin B, and 100mg/day tigecycline. The treatment was effective, and the patient recovered and was discharged from the hospital.Artigo de Periodico Acesso aberto Impact of dental caries on quality of life of school children(2016) Martins, Luiz Gustavo Teixeira; Pereira, Keila Cristina Raush; Costa, Simone Xavier Silva; Traebert, Eliane; Lunardelli, Sandra Espíndola; Lunardelli, Abelardo Nunes; Traebert, JeffersonObjective: To estimate the impact of dental caries on the oral health-related quality of life of school children of public schools of Tubarão, Santa Catarina, Brazil. Material and Methods: A cross-sectional study on a sample of 42310-15 years old students was carried out. The prevalence of dental caries, dental trauma and malocclusion was observed by oral examination based on WHO criteria. The Oral Impact on Daily Performance indicator was used to collect data about the impact on quality of life related to children’s oral health. The Chi-square test was used for bivariate analysis with significance levels set at p<0.05. Prevalence ratios (PR) and confidence intervals (95%) were estimated using log-linear Poisson regression with a robust estimator. Results: The prevalence of dental caries was 55.5%. The prevalence of impact on oral health related quality of life was 45.6%. OIDP dimensions significantly associated with dental caries were eating [PR = 1.45 (95%CI 1.06; 2.00)] (p = 0.021), sleeping [(PR = 2.29 (95%CI 1.15; 4.56)] (p = 0.018) and performing daily activities [PR = 2.57 (95%CI 1.06; 6.22)] (p = 0.036) after adjusting for gender, age and presence of dental trauma and malocclusion. Conclusion: Dental caries was found to be significantly associated with oral health-related quality of life of children in activities such as eating, sleeping, and performing daily activities.Artigo de Periodico Acesso aberto The burden of infectious diseases in the Brazilian Southern state of Santa Catarina(2016) Traebert, Jefferson; Nickel, Daniela Alba; Traebert, Eliane; Escalante, Juan JC; Schneider, Ione JCInfectious diseases are still significant causes of deaths in Brazil. The objective of this study was to estimate the burden of selected infectious diseases in the Brazilian Southern state of Santa Catarina in 2011. An ecological study was conducted. The infectious diseases included were HIV/AIDS, tuberculosis, hepatitis B, hepatitis C, Chagas disease, diarrheal diseases and other infectious diseases. Data were collected from official health information systems. Disability Adjusted Life Years (DALY) were estimated by the sum of Years of Life Lost (YLL) and Years Lived with Disability (YLD). 45,237.33 DALYs were estimated, with a rate of 685.46 DALYs per 100,000 population. 92.9% was due to YLL and 7.1% to YLD. Men and the age range of 0—4 years presented higher burden. The highest burden was attributed to HIV/AIDS. There was a high concentration of burden rates in the coast regions of the state. It could be concluded that more than 90% of the burden was attributed to the early mortality component. The highest burden was observed among men, children under 5 years of age and at the coast regions of the state. The highest levels of burden were due to HIV/AIDS.Artigo de Periodico Acesso aberto Internal construct validity of a Brazilian version of the McMaster Family Assessment Device(2016) Traebert, Eliane; Cremona-Parma, Gabriel Oscar; Traebert, JeffersonObjetivo: Proceder estudo de validação interna de uma versão brasileira do McMaster Family Assessment Device – FAD. Métodos: O questionário foi aplicado em uma amostra de 80 indi- víduos adultos de ambos os sexos. Foi realizada análise fatorial exploratória após análise pré- via de adequabilidade global do método e análise de comunalidades para averiguar pergun- tas que não compartilhavam percentual signi cativo de variância com os fatores de nidos. Para minimizar a quantidade de perguntas que apresentavam elevadas cargas, foi utilizado o método de rotação Varimax com normalização de Kaiser. Resultados: Na versão brasileira em estudo foram mantidas 28 perguntas em quatro novas dimensões contendo 11, 5, 7 e 5 perguntas. Para obtenção de quatro fatores ou dimensões, foram selecionados aqueles com autovalores superiores a dois, o que explicou cerca de 50% da variabilidade dos dados. Con- clusão: A versão brasileira em estudo apresentou comportamento diferente do instrumento original. Observou-se a necessidade de revisar as perguntas e as dimensões do instrumento e também a realização de mais pesquisas com amostras maiores para observar o comporta- mento da escala e sua adequabilidade para utilização no contexto brasileiro.Artigo de Periodico Acesso aberto Proposta de um modelo de avaliação da atenção pública à saúde bucal da criança(2016) Martins, Luiz Gustavo Teixeira; Lacerda, Josimari Telino de; Nickel, Daniela Alba; Traebert, JeffersonThis article proposes a model for quality evaluation of oral health care in children. The conceptual framework for the evaluation matrix consisted of evaluation stu- dies on oral health care services in Brazil and other countries and a survey and review of prevailing public policies for children’s health in Brazil. Two dimensions, Management and Provision, were evaluated in the qua- lity of municipal management of pediatric oral health care. Management included two component dimen- sions, articulation and resources, while Provision inclu- ded two more, “promotion and prevention” and “diag- nosis and treatment”. The evaluation matrix consisted of nine indicators in the Management dimension and nine in the Provision dimension. The indicators were elaborated in workshops with specialists. The model proved appropriate for application in municipalities with different population sizes and allows identifying the areas where managers should improve their actions.Artigo de Periodico Acesso aberto Autoestima e cárie dentária em adolescentes: um estudo seccional(2016) Lunardelli, Sandra Espíndola; Traebert, Eliane; Lunardelli, Abelardo Nunes; Martins, Luiz Gustavo Teixeira; Traebert, JeffersonIntroduction: Dental caries in adolescents remains an important public health problem, but its relationship with psychological factors are poorly studied. Objective: To study the possible association between aspects of self-esteem and dental caries in adolescents. Material and method: A cross-sectional study involving a sample of 409 adolescents from 13 Southern Brazilian municipalities was carried out. Dental caries status was assessed through the World Health Organization criteria. For questions related to self-esteem the Rosenberg Self-Esteem Scale was used. The outcomes were each question of the scale. The chi-square test was used to determine statistical significance of associations. To adjust for confounding variables, the Poisson loglinear with robust estimator was used. Result: Positive associations were observed for the presence of decayed teeth and “At times, I think I am no good at all” (p<0.001), “I wish I could have more respect for myself ” (p= 0.016), “I certainly feel useless at times” (p= 0.022) and negative association with “On the whole, I am satisfied with myself ” (p= 0.022). In the adjusted analysis, adolescents with decayed teeth had a higher prevalence of positive responses to “At times, I think I am no good at all” [(PR= 1.23 (CI 95% 1.05; 1.44)], and negative responses for “On the whole, I am satisfied with myself ” [(PR= 1.12 (CI 95% 1.02; 1.24)]. Conclusion: Aspects of self-esteem were significantly and independently associated with the presence of decayed teeth.Artigo de Periodico Acesso aberto Avaliação do risco cardiovascular segundo os critérios de Framingham em adultos(2016) Della Júnior, Afonso Possamai; Schuelter-Trevisol, Fabiana; Sebold, Fábio Jean Goulart; Nakashima, Leandro; Pereira, Márcia Regina; Trevisol, Daisson JoséObjective: To estimate the risk of a major cardiovascular event within a 10-year period, as well as identify associated risk factors in adults from Tubarão, Santa Catarina, Brazil. Material and Methods: This was a cross-sectional, population-based study applying the Framingham score in 358 adults from Tubarão, Santa Catarina. We aimed to assess the degree of risk and its correlation with variables that may influence cardiovascular risk, such as alcoholism, sedentariness, lifestyle, educational level, in addition to sex, age and smoking habits. The data were analyzed using Pearson’s Chi-square test (÷2) and Fisher’s exact test. The prevalence ratio was used as a measure of association. Results: Among the 358 people surveyed, most were women, Caucasian (87%), with schooling higher than eight years of study (51%), with a steady partner (68.7%), sedentary (60.6%), non-smokers (69.3%), and non-users of alcohol (91.8%). The prevalence of obesity was 26.5%. The mean risk percentage was 2.6% ± 3.7%, with most subjects reaching the low-risk category (94.9%). Male gender (PR = 1.13 [1.07 to 1.20] p <0.001), advanced age (PR = 1.01 [1.00 to 1.01] p = 0.012) and educational level (PR = 0, 99 [0.98 to 1.00] p = 0.039) were factors associated with medium and high risk for cardiovascular events regardless of the outcome. Conclusion: The studied population had a low risk for cardiovascular events. However, the association between potentially modifiable moderate and high risk factors suggests that modification of lifestyle should happen early in this population in order to reduce cardiovascular risks.Artigo de Periodico Acesso aberto Psychometric assessment of the short-form Child Perceptions Questionnaire: an international collaborative study(2016) Thomson, WM; Foster Page, LA; Do, LG; Traebert, Jefferson; Mohamed, AR; Turton, BJ; McGrath, C; Bekes, K; Hirsch, C; del Carmen Aguilar-Diaz, F; Marshman, Z; Benson, PE; Baker, SRObjective: To examine the factor structure and other psychometric characteristics of the most commonly used child oral-health-related quality-of- life (OHRQoL) measure (the 16-item short-form CPQ11-14) in a large number of children (N = 5804) from different settings and who had a range of caries experience and associated impacts. Methods: Secondary data analyses used subnational epidemiological samples of 11- to 14-year-olds in Australia (N = 372), New Zealand (three samples: 352, 202, 429), Brunei (423), Cambodia (244), Hong Kong (542), Malaysia (439), Thailand (220, 325), England (88, 374), Germany (1055), Mexico (335) and Brazil (404). Confirmatory factor analysis (CFA) was used to examine the factor structure of the CPQ11-14 across the combined sample and within four regions (Australia/NZ, Asia, UK/Europe and Latin America). Item impact and internal reliability analysis were also conducted. Results: Caries experience varied, with mean DMFT scores ranging from 0.5 in the Malaysian sample to 3.4 in one New Zealand sample. Even more variation was noted in the proportion reporting only fair or poor oral health; this was highest in the Cambodian and Mexican samples and lowest in the German sample and one New Zealand sample. One in 10 reported that their oral health had a marked impact on their life overall. The CFA across all samples revealed two factors with eigenvalues greater than 1. The first involved all items in the oral symptoms and functional limitations subscales; the second involved all emotional well-being and social well-being items. The first was designated the ‘symptoms/function’ subscale, and the second was designated the ‘well-being’ subscale. Cronbach’s alpha scores were 0.72 and 0.84, respectively. The symptoms/function subscale contained more of the items with greater impact, with the item ‘Food stuck in between your teeth’ having greatest impact; in the well-being subscale, the ‘Felt shy or embarrassed’ item had the greatest impact. Repeating the analyses by world region gave similar findings. Conclusion: The CPQ11-14 performed well cross-sectionally in the largest analysis of the scale in the literature to date, with robust and mostly consistent psychometric characteristics, albeit with two underlying factors (rather than the originally hypothesized four-factor structure). It appears to be a sound, robust measure which should be useful for research, practice and policy.Artigo de Periodico Acesso aberto Preliminary stages of cross-cultural adaptation of the Brazilian Portuguese version of McMaster Family Assessment Device(2016) Traebert, Eliane; Santos, Karoliny dos; Carvalho, Luciana Muller; Silva, Jane da; Traebert, JeffersonObjetivo: Proceder as fases preliminares da adaptação transcultural do Family Assessment Device (FAD) para o português falado no Brasil e analisar sua con abilidade. Métodos: A tradução e a adaptação transcultural do FAD foram realizadas de acordo com métodos internacionalmente recomendados. A versão brasileira foi aplicada em 80 indivíduos que completaram o questionário em duas ocasiões distintas, com intervalo de sete dias. A consistência interna foi avaliada pelo alfa de Cronbach e a reprodutibilidade foi estimada utilizando o método de Bland-Altman. Resultados: A consistência interna obtida foi muito boa (alfa de Cronbach = 0,910). A média das diferenças das dimensões do FAD encontradas no teste de Bland-Altman foi a seguinte: -0,21 (Resolução de Problemas); -0,32 (Comunicação); -0,17 (Papéis); 0,2 (Resposta Afetiva); -0,27 (Envolvimento Afetivo); -0,08 (Controle do Comportamento); -0,02 (Funcionamento Geral). Conclusão: Os processos de tradução e adaptação transcultural foram bem-sucedidos. A aferição da validade de conteúdo é recomendada para o aprimoramento da versão proposta.Artigo de Periodico Acesso aberto Preliminary stages of a cross-cultural Brazilian Portuguese adaptation of a measurement tool for assessing public understanding of human papillomavirus(2016) Manoel, André Luciano; Traebert, Jefferson; Rebello, Luísa Correa; Zapelini, Clávison Martinelli; Trevisol, Daisson José; Schuelter-Trevisol, FabianaThe objective of this study was to conduct the initial stages of the cross- cultural adaptation to Brazilian Portuguese of a scale to measure the level of knowledge about HPV. The stages included: translation from English into the Portuguese spoken in Brazil; synthesis of the translated version; back-translation; analysis by an expert committee; and reliability analysis based on internal consistency and reproducibility. Cronbach’s α coefficient for the instrument was 0.985. Subset analysis produced only minor varia- tions. The correlation coefficients between the individual items and the overall result showed strong positive correlations, except for three items. Reproducibility analysis showed kappa values with substantial or moder- ate agreement for the majority of the items. A preliminary Brazilian ver- sion was obtained with satisfactory results, but other stages are necessary in the process of validation of the Brazilian version.Artigo de Periodico Acesso aberto Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015(2016) GBD 2015 Mortality and Causes of Death Collaborators; Traebert, JeffersonBackground Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns based on sociodemographic measures. Methods We estimated all-cause mortality by age, sex, geography, and year using an improved analytical approach originally developed for GBD 2013 and GBD 2010. Improvements included refinements to the estimation of child and adult mortality and corresponding uncertainty, parameter selection for under-5 mortality synthesis by spatiotemporal Gaussian process regression, and sibling history data processing. We also expanded the database of vital registration, survey, and census data to 14294 geography–year datapoints. For GBD 2015, eight causes, including Ebola virus disease, were added to the previous GBD cause list for mortality. We used six modelling approaches to assess cause- specific mortality, with the Cause of Death Ensemble Model (CODEm) generating estimates for most causes. We used a series of novel analyses to systematically quantify the drivers of trends in mortality across geographies. First, we assessed observed and expected levels and trends of cause-specific mortality as they relate to the Socio-demographic Index (SDI), a summary indicator derived from measures of income per capita, educational attainment, and fertility. Second, we examined factors affecting total mortality patterns through a series of counterfactual scenarios, testing the magnitude by which population growth, population age structures, and epidemiological changes contributed to shifts in mortality. Finally, we attributed changes in life expectancy to changes in cause of death. We documented each step of the GBD 2015 estimation processes, as well as data sources, in accordance with Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER). Findings Globally, life expectancy from birth increased from 61·7 years (95% uncertainty interval 61·4–61·9) in 1980 to 71·8 years (71·5–72·2) in 2015. Several countries in sub-Saharan Africa had very large gains in life expectancy from 2005 to 2015, rebounding from an era of exceedingly high loss of life due to HIV/AIDS. At the same time, many geographies saw life expectancy stagnate or decline, particularly for men and in countries with rising mortality from war or interpersonal violence. From 2005 to 2015, male life expectancy in Syria dropped by 11·3 years (3·7–17·4), to 62·6 years (56·5–70·2). Total deaths increased by 4·1% (2·6–5·6) from 2005 to 2015, rising to 55·8 million (54·9 million to 56·6 million) in 2015, but age-standardised death rates fell by 17·0% (15·8–18·1) during this time, underscoring changes in population growth and shifts in global age structures. The result was similar for non- communicable diseases (NCDs), with total deaths from these causes increasing by 14·1% (12·6–16·0) to 39·8 million (39·2 million to 40·5 million) in 2015, whereas age-standardised rates decreased by 13·1% (11·9–14·3). Globally, this mortality pattern emerged for several NCDs, including several types of cancer, ischaemic heart disease, cirrhosis, and Alzheimer’s disease and other dementias. By contrast, both total deaths and age-standardised death rates due to communicable, maternal, neonatal, and nutritional conditions significantly declined from 2005 to 2015, gains largely attributable to decreases in mortality rates due to HIV/AIDS (42·1%, 39·1–44·6), malaria (43·1%, 34·7–51·8), neonatal preterm birth complications (29·8%, 24·8–34·9), and maternal disorders (29·1%, 19·3–37·1). Progress was slower for several causes, such as lower respiratory infections and nutritional deficiencies, whereas deaths increased for others, including dengue and drug use disorders. Age-standardised death rates due to injuries significantly declined from 2005 to 2015, yet interpersonal violence and war claimed increasingly more lives in some regions, particularly in the Middle East. In 2015, rotaviral enteritis (rotavirus) was the leading cause of under-5 deaths due to diarrhoea (146000 deaths, 118000–183000) and pneumococcal pneumonia was the leading cause of under-5 deaths due to lower respiratory infections (393000 deaths, 228000–532000), although pathogen-specific mortality varied by region. Globally, the effects of population growth, ageing, and changes in age-standardised death rates substantially differed by cause. Our analyses on the expected associations between cause-specific mortality and SDI show the regular shifts in cause of death composition and population age structure with rising SDI. Country patterns of premature mortality (measured as years of life lost [YLLs]) and how they differ from the level expected on the basis of SDI alone revealed distinct but highly heterogeneous patterns by region and country or territory. Ischaemic heart disease, stroke, and diabetes were among the leading causes of YLLs in most regions, but in many cases, intraregional results sharply diverged for ratios of observed and expected YLLs based on SDI. Communicable, maternal, neonatal, and nutritional diseases caused the most YLLs throughout sub-Saharan Africa, with observed YLLs far exceeding expected YLLs for countries in which malaria or HIV/AIDS remained the leading causes of early death. Interpretation At the global scale, age-specific mortality has steadily improved over the past 35 years; this pattern of general progress continued in the past decade. Progress has been faster in most countries than expected on the basis of development measured by the SDI. Against this background of progress, some countries have seen falls in life expectancy, and age-standardised death rates for some causes are increasing. Despite progress in reducing age- standardised death rates, population growth and ageing mean that the number of deaths from most non- communicable causes are increasing in most countries, putting increased demands on health systems.Artigo de Periodico Acesso aberto Characterization of the Epidemiological Profile and Survival of Children with AIDS in Santa Catarina, Brazil, 1988 - 2013(2016) Schuelter-Trevisol, Fabiana; Crocetta, Amanda Sandrini; Magajewski, Flavio Ricardo Liberali; Freitas, Paulo Fontoura; Silva, Helena Caetano Gonçalves; Trevisol, Daisson JoséBackground: It is estimated that survival of children with perinatally transmitted acquired immunodeficiency syndrome (AIDS) in Brazil is around 60 months, and an upward trend has been shown over recent years. The reduction in mortality rates in Brazilian children is mainly attributed to the effectiveness of antiretroviral therapy. Objectives: The aim of this study was to characterize the epidemiological profile and survival rates among children diagnosed with AIDS in the state of Santa Catarina, Brazil. Methods: This was a retrospective cohort study of survival in children aged under 13 years who were reported to have human immunodeficiency virus (HIV) infection in the state of Santa Catarina between 1988 and 2013. The cases were selected from the records of HIV infection cases reported by the Information System for Notifiable and by the Mortality Information System of Santa Catarina, Brazil. Results: We studied 990 children whose median age at diagnosis was 26 months. Among those who died, the survival time after diagnosis was 39.7 months on average, with a median of 16 months. Children’smeanage at death attributed to AIDS was 73.8 months, with a median of 55 months. Of the 990 surveyed children, the median survival time was 263 months, and 14.7% died of AIDS. The chance of survival at 60 months was estimated to be 88.1%. Conclusions: The studied indicators suggest that the AIDS epidemic in children showed a decreasing tendency in terms of the incidence and mortality rates with tendency, along with an unexpected growth trend in lethality rate in the last period.Artigo de Periodico Acesso aberto Prevalência de hiperglicemia em idosos: um estudo de base populacional(2016) Espanhol, Felipe Zancan; Oliveira, Rita de Cássia Schmitz Mendes de; Silvano, Gustavo Paes; Manoel, André Luciano; Silveira, Laise Rodrigues; Schuelter-Trevisol, Fabiana; Trevisol, Daisson JoséAims: To evaluate the prevalence of hyperglycemia and associated factors in the elderly population of a municipality in southern Brazil. Methods: Cross-sectional population-based study, carried out with the elderly (≥60 years) living in the city of Tubarão, state of Santa Catarina, Brazil, from September 2010 to May 2011. Participants were selected by simple random sampling. The elderly were registered by the Community Health Agents of the Family's Health Strategy Program. Sociodemographic data (age, gender, skin color, marital status, employment status and education), behavioral data (physical activity, alcohol use and smoking) and clinical data (obesity, drug use and family history of diabetes) were recorded. After answering these questions the participants were scheduled to attend the clinic for blood collection and anthropometric measurements. The prevalence of hyperglycemia was assessed from fasting blood glucose tests, and individuals with values ≥126 mg/dL or use of hypoglycemic drugs were considered hyperglycemic. To assess the association between the variables of interest, the chi-square test was applied. The pre-determined confidence interval was of 95% and the error α of 5%. Results: Eight hundred thirty-three elderly patients were included, and 220 were considered hyperglycemic according to the methodology criteria (prevalence of 26.4%). Of the patients included in the hyperglycemia group, 190 were using oral hypoglycemic drugs, and of these, 112 had also fasting glucose ≥126 mg/dL, while in 78 fasting glucose was <126 mg/dL. Also in the hyperglycemia group, 30 patients had fasting glucose ≥126 mg/dL and were not on hypoglycemic treatment. Having parents diagnosed with diabetes and being obese were associated with the presence of hyperglycemia. Conclusions: This study suggests that a large portion of the elderly population has fasting hyperglycemia, requiring a wider evaluation for diabetes mellitus.Artigo de Periodico Acesso aberto Adverse birth outcomes and oral health(2016) Traebert, Eliane; Martins, Luiz Gustavo Teixeira; Lunardelli, Sandra Espíndola; Lunardelli, Abelardo Nunes; Traebert, JeffersonIt is vital to improve the understandingof early child’s oral health determinants and conse-quent identification of interventions and behaviorsthat can be modified with health promotion activi-ties since birth. Authors have suggested that proper fetal growth and adequate development in the first two years of life are determinants ofhealth, not only at childhood but also in later life.David Barker’s studies conducted in the 1980s have suggested that the events of the intrauterineperiod or during early childhood have long-termeffects on morbidity and mortality from chronicdiseases.On the other hand, the Life-Course Theory emphasizes the infancy period, based on the accu-mulation of environmental, social, and behavioralrisks in life, without disregarding Barker’s pre-mises, to strengthen the interaction between bio-logical and social factors of the different stages of life, more than the current adult lifestyle. However, little research has been carried outfocusing on these ideas to determine children’s oralhealth. There is a scarcity of longitudinal studies,such as population-based cohort studies, that aimto understand the determination of the oral health-disease process and the complex interactionbetween social environment and biological and behavioral aspects. The study published by thisimportant journal has contributed to bring thisissue to the agenda.