Avaliação do perfil epidemiológico e dos desfechos clínicos de pacientes com tuberculose multirresistente no estado de Santa Catarina entre os anos de 2009 e 2019
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Data
2022-06-13
Tipo de documento
Artigo Científico
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Área do conhecimento
Ciências da Saúde
Modalidade de acesso
Acesso fechado
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Autores
Soccal, Fernanda de Araujo
Miguel, Natalia Blanco
Fernandes, Camilo
Silva, Franciele Cascaes da
Orientador
Fernandes, Camilo
Coorientador
Silva, Franciele Cascaes da
Resumo
Objetivo: Traçar o perfil epidemiológico e avaliar os desfechos clínicos de pacientes com tuberculose multirresistente no Estado de Santa Catarina, notificados entre os anos de 2009 e 2019. Métodos: Estudo observacional transversal, utilizando banco de dados do Sistema de Informação de Tratamentos Especiais da Tuberculose, do qual fizeram parte pacientes notificados com tuberculose multirresistente em Santa Catarina entre janeiro de 2009 e dezembro de 2019. Resultados: Dentre 265 participantes, as características sociodemográficas de maior prevalência foram idade entre 20 e 59 anos (90,2%), sexo masculino (69,8%), etnia branca (85,2%) e com escolaridade menor ou igual a 7 anos (65,6%). Houve maior número de notificações fora da Grande Florianópolis (66,4%), pacientes não assalariados (58,5%), com forma clínica pulmonar (91,6%), não bilateral (56,2%), com tratamento completo (69,8%). Os agravos mais prevalentes foram uso de drogas ilícitas (23,4%), tabagismo (30,9%), etilismo (23,8%), AIDS (16,6%) e Diabetes Mellitus (9,5%). Sobre os desfechos clínicos, evidenciou-se significância estatística na associação de etnia (p=0,020) e escolaridade (p=0,009) com desfecho clínico “tratamento completo”. Conclusão: O perfil encontrado é composto, majoritariamente, por homens, etnia branca, entre 20 e 59 anos, escolaridade menor ou igual a 7 anos, não assalariados, notificados fora da Grande Florianópolis, com forma clínica pulmonar, não bilateral e que completaram tratamento.
Objective: To describe the epidemiological profile and evaluate the clinical outcomes of patients with multidrug-resistant tuberculosis in the state of Santa Catarina, notified between 2009 and 2019. Methods: A cross-sectional observational study, using the “Sistema de Informação de Tratamentos Especiais da Tuberculose” (SITETB) database, which included all reported patients with multidrug-resistant tuberculosis in Santa Catarina state between January 2009 and December 2019. Results: Among 265 participants, most prevalent sociodemographic characteristics were age between 20 and 59 years (90.2%), male (69.8%), white ethnicity (85.2%) and with 7 years or less years of schooling (65.6%). There was a greater number of notifications in regions outside of Grande Florianópolis (66.4%), unsalaried patients (58.5%), with a predominance of pulmonary (91.6%) and non-bilateral (56.2%) clinical forms, with complete treatment (69.8%). Most prevalent comorbidities were the use of illicit drugs (23.4%), smoking (30.9%), alcoholism (23.8%), AIDS (16.6%) and Diabetes Mellitus (9.5%). Regarding clinical outcomes, there was statistical significance in the association of ethnicity (p=0.020) and education (p=0.009) with the clinical outcome “complete treatment”. Conclusions: The patients profile is mostly composed of men, of white ethnicity, between 20 and 59 years old, with 7 or less years of schooling, unsalaried, reported in regions outside of Grande Florianópolis, with pulmonary and non-bilateral clinical form, who completed the treatment.
Objective: To describe the epidemiological profile and evaluate the clinical outcomes of patients with multidrug-resistant tuberculosis in the state of Santa Catarina, notified between 2009 and 2019. Methods: A cross-sectional observational study, using the “Sistema de Informação de Tratamentos Especiais da Tuberculose” (SITETB) database, which included all reported patients with multidrug-resistant tuberculosis in Santa Catarina state between January 2009 and December 2019. Results: Among 265 participants, most prevalent sociodemographic characteristics were age between 20 and 59 years (90.2%), male (69.8%), white ethnicity (85.2%) and with 7 years or less years of schooling (65.6%). There was a greater number of notifications in regions outside of Grande Florianópolis (66.4%), unsalaried patients (58.5%), with a predominance of pulmonary (91.6%) and non-bilateral (56.2%) clinical forms, with complete treatment (69.8%). Most prevalent comorbidities were the use of illicit drugs (23.4%), smoking (30.9%), alcoholism (23.8%), AIDS (16.6%) and Diabetes Mellitus (9.5%). Regarding clinical outcomes, there was statistical significance in the association of ethnicity (p=0.020) and education (p=0.009) with the clinical outcome “complete treatment”. Conclusions: The patients profile is mostly composed of men, of white ethnicity, between 20 and 59 years old, with 7 or less years of schooling, unsalaried, reported in regions outside of Grande Florianópolis, with pulmonary and non-bilateral clinical form, who completed the treatment.
Palavras-chave
Tuberculose, Mycobacterium tuberculosis, Tuberculose Resistente a Múltiplos Medicamentos, Resistência a Medicamentos