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Artigo Científico Acesso embargado Tendência temporal de internações por glaucoma no estado de Santa Catarina entre 2013 e 2022(0024-06) VEIGA, Gabriela; RIBEIRO, Emily Bruna JustinoRESUMO O glaucoma é uma neuropatia óptica crônica, caracterizada pela perda do campo visual e lesão do nervo óptico, que pode levar a um dano progressivo e irreversível ao disco óptico e as camadas finas nervosas da retina. É considerado a terceira maior causa de cegueira na população mundial, sendo responsável por 2,4 milhões de novos casos ao ano e ocasionou, segundo DATASUS, no Brasil entre 2013 e 2022 43,999 internações. Objetivo: O objetivo deste estudo é analisar a tendência temporal de internações por glaucoma no estado de Santa Catarina entre 2013 e 2022. Métodos: Trata-se de estudo de tendência temporal de internações por glaucoma no estado de Santa Catrina com dados do Departamento de Informática do Sistema Único de Saúde. A Análise estatística por regressão linear simples, com variação média anual das taxas (β) e variação percentual, considerando significativo p<0,05. Resultados: Foram analisadas 2.665 casos de internações por glaucoma em adultos e idosos em Santa Catarina, de 2013 a 2022. Conclusão: Conclui-se ao avaliar as taxas de regressão uma tendência de aumento na taxa geral de internação (β 0,78 p <0,007) no período analisado para sexo feminino e masculino, com taxa média de 3,77 internações e redução de 5,1% entre 2013 e 2022. Consoante a isto, no sexo masculino foi observado aumento das internações apenas na faixa etária de 50 a 59 (p <0,004), para todas as demais idades e para o sexo feminino foi observado aumento.Artigo Científico Acesso fechado Prose palpebral congenita e as complicações do tratamento(1123-11) CAMARGO, Maria Antônia Vicente de, JUNIOR, Astor GrumannObjetivo: Analisar as complicações do tratamento da ptose palpebral congênita atendidos em hospital de referência estadual, no período de 2010 a 2022. Métodos: Estudo de coorte histórica, realizado no hospital público de referência da grande Florianópolis. A população do estudo incluiu pacientes submetidos ao tratamento cirúrgico de elevação frontal da ptose palpebral congênita, no período compreendido entre janeiro/2010 a dezembro/2022, com análise descritiva de características clínicas e epidemiológicas. Resultados: 54 pacientes constituíram a amostra, cuja maioria era do sexo masculino 75,9%, com média de idade de 5,5 (desvio padrão) anos. Em relação à lateralidade, 12 (22,2%) pacientes apresentaram ptose apenas no olho direito, 20 (37%) apenas no olho esquerdo e 22 (40,7%) em ambos os olhos. Lagoftalmo foi a principal complicação observada, sendo que 35 pacientes (64,81%) apresentaram complicações transitórias e 19 (35,19%) com complicações definitivas. Conclusão: A avaliação da ocorrência de complicações no tratamento cirúrgico, a necessidade de reintervenção cirúrgica e as complicações do tratamento em relação ao tempo de pós-operatório são aspectos cruciais para melhorar os resultados clínicos e a segurança dos pacientes.Artigo Científico Acesso embargado Tendência temporal dos acidentes por Loxosceles no estado de Santa Catarina no período 2007 - 2015(2017) Alamino, Marília MedeirosIntroduction: Spiders of the genus Loxosceles are of high health risk associated dermonecrotic lesions and systemic reactions, being more prevalent in regions with a tropical climate. Objective: To analyze temporarily the accidents with Loxosceles in the State of Santa Catarina from 2007 to 2015. Method: Ecological study using the SINAN database from 2007 to 2015, related to time, regions, age group, gender, time of bites, classification and evolution in the time-event correlation criteria. Results: The profile of the one who suffers accident was predominantly female, young, from the regions of the west catarinense, middle west and upland north. Respecting incidence rates, there was stability. Seasonality was confirmed, with predominance in spring and summer. Outcomes had high rates for cure and demand for early and late medical care. Conclusion: Knowing the epidemiological profile of the notifications it is possible to develop public politics that are more effective for prevention and more qualified for the attention of the most serious cases of Loxosceles accidents.Artigo Científico Acesso fechado Análise da correlação dos índices compostos de atividade da doença e a concordância entre os diferentes estados de atividade em pacientes com artrite reumatoide(2017) Fontana, tayssaIntroduction: Rheumatoid arthritis (RA) is an inflammatory joint disease of systemic involvement and varied evolution, which uses different disease evaluation scores. It is essential that these instruments be evaluated according to the disease, so that the treatment algorithms can be applied independently. Objective: To analyze a correlation of disease activity indexes (ICADs) and a concordance between different states of activity in patients with Rheumatoid Arthritis. Method: Cross-sectional study based on 100 patients of outpatient care from a multicenter prospective cohort study. Approved by CEP UNISUL. Statistical analysis by the SPSS 18.0 program, using the Pearson Correlation Coefficient and McNemar-Bowker Concordance, considering significance level p˂0,05. Results: Majority female patients (86%), with an average age of 54 years, who were active in their jobs (53%) and had a positive rheumatoid factor in 65%. The average values of the ICADs were DAS-28 (3.6), DAS-28 PCR (3.0), SDAI (13.4), CDAI (12.5) and RADAI (3.5), respectively. Many were classified with moderate disease activity of the disease. The degree of correlation was very strong (> 0.8) and strong (between 0.8 and 0.6) in most ICADs and a concordance of remission DAS-28PCR ranged from 41.3% to 54.3% with the other ICADs. Conclusion: The ICADs presented a strong correlation with each other, as well a level of similarities in the classification of the different degrees of activity. These results confirm that in different patients with RA, the ICADs serve to define active disease and to aid in the treatment strategy, so it is not imperative to use only a single evaluation score.Monografia Acesso fechado Associação entre a indicação de procedimento de endoscopia digestiva alta e o resultado obtido, em um hospital terciário da Grande Florianópolis(2017) Machado, Matheus Camilo MartinsIntroduction: The esophagogastroduodenoscopy (EGD) is a procedure used for diagnostic and therapeutical purposes in the upper gastrointestinal tract. In Brazil, it has a low financial cost and a high cost-benefit, being thus increasingly used. Therefore, it’s important to analyse if the EGDs are being referred in a rational, cohesive and logical manner, or if changes are necessary. Objective: To investigate the association between indication of EGD and outcome. Methods: This cross-sectional study was conducted in the Endoscopic Unit of the Hospital Governador Celso Ramos in Florianópolis. 1080 EGDs were evaluated in the period between January and June of 2016. The data were collected through the patients’ electronic records. Statistical analysis was done using the chi-squared test, and a value of p < 0.05 was considered statistically significant, having a risk ratio with a 95% confidence interval. Results: Of the EGDs analysed, 57,5% were performed in women, and 48,1% in patients between the ages of 46-65. Of the indications, 43,6% were gastric complaints. 4,7% had no identifiable indication. The gastric and duodenal outcomes were observed in 46,7% of EGDs; neoplasms, in 1,4%. A normal outcome was seen in 9,5%. Gastric complaints had a correspondence with gastric and duodenal diseases of 59,2%. Conclusion: Most indications were due to gastric complaints and the commonest outcomes were gastric and duodenal diseases, and those two had the biggest correspondence with each other. Indication and outcome corresponded with each other in 47,5% of the EGDs.Artigo Científico Acesso embargado Tendência temporal de internação por infarto agudo do miocárdio nos estados do Sul do Brasil no período de 2008 a 2016(2017) Okabe, Jessica MayumiAcute Myocardial Infarction (AMI) is responsible for high hospitalization rates, one of the major causes of morbidity and mortality. The objective of this study was to analyze the temporal trend of hospitalization for AMI in the southern Brazilian states from 2008 to 2016. Ecological study of time series of hospitalization for acute myocardial infarction, from the Database of the Department of Informatics of the Unified Health System. The hospitalizations for AMI (CID -10 - code I 21.9) were selected in the population residing in the States of Paraná, Santa Catarina and Rio Grande do Sul were selected according to sex and age group from 2008 to 2016. Simple linear regression was performed. This study was approved by the Research Ethics Committee of the Southern University of Santa Catarina. Between 2008 and 2016, there were 154,828 hospitalizations for AMI in the southern region of Brazil. There was an average annual increase of 4,261 cases / 100,000 in the rate of hospitalization for AMI in the Southern Region (Paraná β = 1.064; Santa Catarina β = 1.159, Rio Grande do Sul β = 1.156). Among men increased from 15,732 cases / 100,000 and in women 8,553 cases / 100,000 (p <0.001). The age groups between 40-49 years and 70-79 years for both sexes present an increasing trend (p <0.005). The age group older than 80 years in males had the highest absolute variation 32,945.31 admissions in 2008 and 35,152,95 admissions in 2016. The study showed an upward trend in hospitalization rates for AMI in the Southern Region, by sex and age groups above 30 years for both sexes.Artigo Científico Acesso embargado Impacto tardio do tratamento laparoscópico da Endometriose Profunda Infiltrativa com ressecção segmentar colorretal(2017) Rocha, Antonio MatosABSTRACT – Background – Deeply infiltrating endometriosis may have an important impact on patient's quality of life and fertility. Segmental resection is a therapeutic option with positive results reducing of symptoms but still with no proven functional effects. Aim – To evaluate the late impact of laparoscopic treatment of deep infiltrative endometriosis with colorectal segmental resection. Methods – Prospective cohort study with 46 patients submitted laparoscopic treatment for deep infiltrative endometriosis with colorectal segmental resection between 2013 and 2016. Gynecological and intestinal symptoms and fertility were assessed in the preoperative period, 3 and 12 months or more after the procedure. Data were analyzed using the McNemar chi-square test. The ethics committee of the educational institution approved the study. Result – In the preoperative interview, the prevalence of gynecological (87%), intestinal (80.4%) and infertility symptoms (45.6%) were assessed. In the third postoperative month, the prevalence of gynecological symptoms (dysmenorrhea, deep dyspareunia and chronic pelvic pain) was reduced by more than 86% (p <0.001) and of intestinal symptoms, tenesmus and dyschezia, of 82.4% and 69.2%, respectively (p = 0.001 and p = 0.002). After 12 months or more of postoperative period, was observed reduction on dysmenorrhea (60.03%), deep dyspareunia (45.39%) and chronic pelvic pain (61.92%) in addition to dyschezia (64.8%) when compared with the preoperative period (p <0.05). The total pregnancy rate was 57.1% and the spontaneous pregnancy rate was 47.6%. Conclusion - Treatment of deeply infiltrating endometriosis with colorectal segmental resection provided early and late relief of gynecological and intestinal symptoms. The results suggest a positive impact on fertility in infertile patients.Monografia Acesso fechado Prevalência e fatores associados a hipertensão arterial sistêmica e uma capital do Sul do Brasil(2017) Silva, Matheus de BemThe increased in the prevalence of hypertension is associated with active and structural target organs that lead to increased complications and risks of death from cardiovascular problems. Knowing the prevalence of hypertension and the associated factors are relevant for prevention and treatment. To know the prevalence and the factors associated with Systemic Arterial Hypertension in a capital of Southern Brazil. Cross-sectional study of the adult evaluation of the population, both sexes, interviewed in 2013 (VIGITEL). The data was obtained from access to the micro data research, processed by DATASUS and analyzed by the SPSS 18.0 program, using the Chi-square test. The association measure was used for a prevalence ratio, with confidence interval (95% CI) and p<0.05. Approved by CEP-UNISUL. A prevalence of hypertension was 32.2%. Prevalence of male (62.1%), age greater than or equal to 60 years (39.3%) schooling over 12 years (39.2%), obesity (16.8%), dyslipidemia (26.2% ), diabetes (9.1%), high salt intake (14.7%), physical inactivity (17.6%), smoking (11.2%) and abusive alcohol consumption (12.7%). There was an association with statistical significance between hypertension and age 40, low levels of education, being obese or not, having dyslipidemia and diabetes, not physically active and making abusive use of alcohol. The majority of hypertensive patients are male adults, older than 40 years, with less than 8 years of schooling, obese or not, dyslipidemic and diabetic, not physically active and marking abusive alcohol use. Cardiovascular risk factors are high and calls attention to a need for a systematic approach of the prevention and control of hypertension.Artigo Científico Acesso embargado Perfil epidemiológico e desfechos associados às corionicidades em gestações gemelares(2017) Cortez, Tamires AiexObjective: To analyze the epidemiological profile and outcomes associated with twin pregnancy and its chorionicities. Methods: A retrospective cross-sectional study analyzing the twin pregnancies in a teaching Public Hospital, in a six-year period, through data of 167 pregnant women. The information was collected in medical records and in a database. Statistical analysis according to chorionicity and amnionicity for the obstetric outcomes and calculated the relationships using the Mann-Whitney, Chi-Square test and Prevalence Ratio. Results: The prevalence of twin pregnancies was 1.5%. The type of placentation was dichorionic and diamniotic in 57.7%, monochorionic and diamniotic in 25.6% and monochorionic and moniamniotic in 6.0%. The dichorionic gestation was shown to be a protective factor for prematurity, low birth weight, and low gestational age of the first twin. Conclusion: Knowing the outcomes associated with twinning and their chorionicities, one should consider these particularities, since their relationships with prematurity and low birth weight worsen the fetal prognosis.Monografia Acesso fechado Estudo da prevalência e dos fatores associados à hipovitaminose D na população portadora de HIV na região metropolitana de Florianópolis(2017) Schirmbeck, Aline RiffelIntroduction: HIV infection has a high incidence in the metropolitan region of Florianópolis and, currently, studies have shown it to be a chronic inflammatory disease with potential association with hypovitaminosis D. Objective: To identify the prevalence and factors associated with hypovitaminosis D in the population with HIV. Methods: A cross-sectional study conducted in the Hospital Regional de São José with 160 HIV patients from January 1, 2015 to December 31, 2016, based on information obtained in medical records. Results: In the studied population, there was a predominance of women (53.1%), aged less than 50 years (70.6%) and Caucasians (87.3%). The prevalence of hypovitaminosis D was 56.3%, 20.6% with deficiency and 35.6% with insufficiency. A statistical association was observed between hypovitaminosis D and renal insufficiency (p = 0.04). It was also observed a protective relationship with tenofovir (p = 0.03) and associative tendency with zidovudine use (p = 0.06).Conclusion: This is one of the first studies on the subject conducted in the southern region of the country, with a prevalence rate of 56%. The results reinforce the importance of monitoring vitamin D levels in patients with HIV, especially those with renal impairment and history of use of zidovudine.Artigo Científico Acesso embargado Tendência temporal de internação por queimadura no Sul do Brasil(2017) Favassa, Marina TherezaResumen Objetivo: Evaluar la tendencia temporal de internación por quemadura en el Sur de Brasil, en el período de 2008 a 2016. Metodos: Estudio ecológico de series temporales, realizado a partir del Banco de Datos del SIH-SUS, con internaciones de residentes del Sur de Brasil, de 2008 a 2016. Las tasas de internaciones fueron estandarizadas por los estados del Sur, sexo y grupo de edad y se realizó una regresión lineal simple para estimar las tendencias de internación. Aprobado por el Comité de Ética en Investigación-UNISUL, CAAE nº 62117416.3.0000.5369 Resultados: En el período estudiado ocurrieron 37.571 internaciones. La tasa de internación por quemadura en 2008, inicio del período, fue 13,11 internaciones por 100.000 habitantes, finalizando el período (2016) con tasa de 14,60 / 100.000 habitantes, manteniendo constante en el período. En el sexo masculino las tasas fueron superiores, iniciando el período con 15,87 / 100.000, finalizando la serie histórica con 19,76 / 100.000. En el femenino, la tasa se ha mantenido lineal durante el período. Se verificó que el Paraná presentó las mayores tasas en relación a Santa Catarina y Rio Grande do Sul. El grupo de edad más afectado fue de 0-19 años. Conclusión: Hubo tendencia de estabilidad en la tasa general de internación. El sexo masculino y el grupo de edad de 0-19 años fueron los más afectados por quemaduras en el sur de Brasil. El Paraná se quedó siendo el estado con mayores tasas de internación cuando comparado a los otros dos estados. Abstract Objective: To evaluate the temporal trend of hospitalization for burns in the South of Brazil, from 2008 to 2016. Methods: Ecological study of time series, carried out from the Database of the SIH-SUS, with hospitalizations of residents of the South of Brazil, from 2008 to 2016. The hospitalization rates were standardized by the southern states, sex and age group and a simple linear regression was performed to estimate the hospitalization trends. Approved by the Research Ethics Committee-UNISUL, CAAE nº 62117416.3.0000.5369. Results: During the study period, 37,571 hospitalizations occurred. The hospitalization rate for burns in 2008, beginning of the period, was 13.11 hospitalizations per 100,000 inhabitants, ending the period (2016) with a rate of 14.60 / 100,000 inhabitants, remaining constant in the period. In males the rates were higher, starting the period with 15.87 / 100,000, finishing the historical series with 19.76 / 100.000. In the female, the rate remained linear during the period. It was verified that Paraná presented the highest rates in relation to Santa Catarina and Rio Grande do Sul. The most affected age group was 0-19 years. Conclusion: There was a trend towards stability in the general hospitalization rate. The male gender and age group of 0-19 years were the most affected by burns in the South of Brazil. Paraná was the state with the highest hospitalization rates when compared to the other two states.Artigo Científico Acesso embargado Fatores de risco relacionados à necessidade de reanimação neonatal na sala de parto de uma maternidade de Santa Catarina(2017) Espíndola, Lílian Dressler deObjetivo: Determinar os fatores de risco associados aos procedimentos de reanimação em recém-nascidos nascidos na sala de parto de uma maternidade de Santa Catarina. Métodos: Estudo observacional, com delineamento caso controle. Foi obtido uma amostra de 307 casos e 307 controles no período entre julho a dezembro/2016. Medida de associação o Odss Ratio (OR) com os respectivos intervalos de confiança (IC 95%), nível de significância estabelecido é de p <0,05. Resultados: Foi encontrado uma prevalência de 16% de reanimados. Aspiraração de vias aéreas foi a manobra mais utilizada e apenas 1,3% precisou de manobras agressivas. Adolescencia, líquido meconial, apresentações anômalas, partos cesáreos e sexo masculino são características mais frequentes nos recém-nascidos reanimados. Doenças crônicas maternas, gemelaridade, número de consultas pré-natais e tempo de ruptura das manobras não se mostraram significantes. Prematuridade e baixo peso tiveram grande correlação com a reanimação. Apenas 7 recém-nascidos foram a óbito na sala de parto e mais 7 até o sexto dia de vida. Conclusão: Parto na adolescência, mecônio, apresentação anômala, parto cesáreo e sexo masculino são fatores de risco para a reanimação. Recém-nascidos pré-termos e aqueles com <2500g possuem maior chance de serem reanimados. A qualidade do atendimento é fundamental para a melhora do Apgar e para a baixa mortalidade.Monografia Acesso fechado Fatores associados à neoplasia não invasiva de alto grau em pólipos adenomatosos de pacientes que realizaram colonoscopia por indicação de rastreamento de carcinoma colorretal(2017) Souza, Julia Koerich deIntroduction: Intestinal adenomatous polyps are precursor lesions of colorectal carcinoma (CRC), one of the most common types of cancer among men and women. Screening and appropriate treatment of polyps is able to reduce incidence and mortality by CRC. Objective: To identify the factors associated with high-grade neoplasia in adenomatous polyps of patients 50 years of age or older who underwent colonoscopy for CRC screening. Methods: Case-control study with 216 individuals with adenomatous polyps who underwent colonoscopy in private practice in Florianópolis, separated in two groups according to the presence or absence of high grade neoplasia. Data obtained from electronic medical records. Statistical analysis SPSS 18.0, Chi-square test, and p≤0.05. Oddis Ratio (OR) with 95% CI. Approved by CEP UNISUL. Results: There was no statistically significant relationship between sex; Age; Genre; Family history; Previous polypectomies; Number of polyps; And high-grade neoplasia. Weak association with non-polypoid morphology (OR=2,875 and p=0,051) and statistical significance with polyp size ≥1cm (OR=26.147 and p<0.01), villous or tubulo-villous histology (OR=7 and p <0.01) and location of the polyp in the left colon (OR=37.766 and p<0.01). Conclusion: The factors associated with high-grade neoplasia in colon adenomas include polyp size greater than or equal to 1 cm, villous or tubulo-villous histology, the location of the polyp in the left colon, and non-polypoid morphology.Artigo Científico Acesso embargado Prevalência e fatores associados à ideação suicida na procura por atendimento psiquiátrico em uma clínica-escola(2017) Rubini, Marina RochaSuicide is a phenomenon in all regions of the world, so it is one of the priorities of the mental health program of the World Health Organization (WHO). Clinical features such as underlying psychiatric illness, use of psychoactive substances, personal history of suicidal events, and family history of suicide are data that help identify groups at higher risk. The general objective of the study is to know the prevalence and factors associated with suicidal ideation in the search for psychiatric care. This is a cross-sectional study, carried out at the Policlínica Municipal de Palhoça, Grande Florianópolis / SC. Data from 228 patients were included, and a data collection was performed by means of medical records. The most prevalent complaints were depressive mood (57.9%), irritability and aggressiveness (47.4%), anhedonia (37.3%), insomnia (31.6%), visual and auditory hallucinations (26.3%) and social isolation (21.1%). When compared to the middle age group of 35-59 years, patients between the ages of 18 and 34 have a 2.73 times greater chance of suicidal ideation and those aged 60 or over are about 5 times more likely to be suicidal. It was concluded that patients who complained of depressive mood (OR 3.98), anhedonia (OR 1.87) and, finally, visual and auditory hallucinations (OR 3.98), had more chance of suicidal ideation.Artigo Científico Acesso embargado Efeito anti-hiperalgésico promovido pelo exercício aeróbico contínuo e intervalado em camundongos submetidos em um modelo de síndrome da dor regional complexa do tipo-I(2017) Sousa, Ana Laura GarciaBACKGROUND AND OBJECTIVE: Aerobic physical exercise is an alternative to adjuvant treatment of chronic pain. The objective of this study was to evaluate the effects of continuous aerobic exercise (EAC) and interval aerobic exercise (EAI) on mechanical hyperalgesia in mice submitted to the chronic post-ischemic pain model (DPIC). METHODS: Male Swiss mice submitted to ischemia and reperfusion (IR) were used. After the seventh day of IR, exercise sessions were started. Each group performed one session per week and mechanical hyperalgesia was evaluated on days 7, 14 and 21 after induction. Naloxone at doses (1 mg / kg i.p., 10 mg / kg i.p.) and morphine (5 mg / kg s.c.) were administered. In the evaluation of mechanical hyperalgesia the Von Frey filament (0.6 g) was used. RESULTS: The velocity of 16 m / min and the time of 30 minutes presented the best antihyperalgesic effect after the session. When comparing the antihyperalgesic effect between EAC and EAI, EAI at speeds of 16 m / min and 19 m / min for 30 minutes obtained the most lasting analgesic effect for 5 hours while EAC at 16 m / min for 30 minutes per one hour. CONCLUSION: This study indicates that treadmill EFA reduces the mechanical hyperalgesia generated by DPIC in mice. The EAI generates greater analgesic effect after the run in relation to the EAC. Opioid receptors are involved only in EAC. We suggest new studies on the mechanisms involved in analgesia induced by EAI.Monografia Acesso fechado Fatores associados ao óbito em pacientes submetidos à laparotomia pós trauma abdominal no Hospital Regional de São José(2017) Schmitz, José Ricardo GramsIntroduction: Abdominal trauma is an important cause of morbidity and mortality, and knowledge of the epidemiological and clinical context is necessary to assist in the initial evaluation of the patient. The standardization of criteria for surgical intervention or the choice of conservative treatment are extremely important to avoid complications or mortality due to abdominal trauma. Objective: To identify the factors associated with death in patients submitted to laparotomy after abdominal trauma at the Regional Hospital of São José. Methods: A case-control study analyzing 202 patient charts of abdominal trauma victims submitted to an exploratory laparotomy using an instrument for collecting data. Data Analysis in SPSS 18.0, chi-square test and p<0.05. Prevalence ratio with 95% CI. The study was approved by REC. Results: Prevalence of mortality in male patients (91%), younger than 55 years (82.4%), blunt trauma (58.8%), automobilistic accident (52.9%), Glasgow ≤8 (59.1%), SBP≥90mmHg, FC ≥100bpm (52.4%), Hb <10g/dL (52%), multiple lesions (61.8%), spleen and liver injuries (38.2% each), extra abdominal injuries (76.5%), associated thoracic trauma (64.7%), presence of complications (94.1%), hypovolemic shock (61.8%) and damage control surgery (51.5%). Conclusion: The factors associated with mortality with statistical significance (p <0.05) were advanced age, blunt trauma, altered GCS, SBP <90mmGh, Hb <10g/dL, multiple lesions, solid viscera (spleen, kidney and pancreas), associated traumas (thoracic and cranioencephalic), postoperative complications (hypovolemic / hemorrhagic shock, CRP, acute renal failure, acute respiratory insufficiency) and the need for damage control surgery.Artigo Científico Acesso embargado Associação entre atividade clínica e biomarcadores em pacientes com Doença de Crohn sob terapia de manutenção(2017) Gentil Junior, Adir CardosoIntroduction: Crohn's Disease, alongside Ulcerative Colitis, form the group of diseases called Inflammatory Bowel Diseases. The clinical course varies, but the main symptoms are abdominal pain and diarrhea. Its main biomarkers of activity are C-Reactive Protein (CPR) and Faecal Calprotectin (FC). Aim: This study aims to evaluate the association between the clinical activity of Crohn's Disease and the biomarkers, CRP and CF in patients under maintenance therapy. Methods: This is a cross-sectional observational study. In the research, data were collected from medical records of this institution, being included only patients over 18 years old and whom had CPR and FC measurement performed. The variables analyzed were: sex, age, FC dosage, CRP dosage and presence of symptoms (diarrhea, abdominal pain, arthritis / arthralgia and fistulas). Results: 36 patients were included in the study, 19 of which were male and 17 female. The mean age was 43.74 years (15.6). Regarding the clinical characterization, 25 patients had no symptoms and 11 patients were symptomatic, five of which were due to abdominal pain, five due to diarrhea and one due to symptoms that were not valid for the study. As for the association between symptoms and biomarkers, it was statistically significant between CRP and symptomatic patients (p = 0.039), CRP and symptomatic patients in the female group (p = 0.025) and CRP and patients with diarrhea in the female group (p = 0.038).Conclusion: CPR is associated with clinical activity on CD patients, especially women. Although not statistically significant, FC is higher in those who belong to the male group with abdominal pain and diarrhea. Both are important non-invasive biomarkers to control the disease activity and treatment effectiveness.Monografia Acesso fechado Avaliação da gravidade das lesões coronarianas e do comprometimento do miocárdio pós Infarto Agudo do Miocárdio (IAM) relacionadas com a atividade física(2017) Sartor, Evelim de MedeirosIntroduction: The regular practice of physical exercise offers a relevant protective effect, especially if combined with the prevention of other Risk Factors Objective: Evaluate the severity of coronary lesions and myocardial compromise after AMI related to physical activity. Methods: This cross-sectional study included 134 patients who were admitted with a first infarction at the Santa Catarina Institute of Cardiology (ICSC). Data were collected through interview and analysis of medical records. Approved in Ethical Committee in Research of UNISUL and ICSC. Results: The mean age was 58.39 ± 10.68 years, male predominance (63.6%), Hypertension (61.9%), smoking (29.9%) and total Baecke score 4.86 ± 1.34. Patients who consumed alcohol presented a higher Baecke score (5.28 ± 1.32) when compared to those who did not drink (4.70 ± 1.31). Conclusion: There was no correlation between the severity of the lesions and myocardial involvement related to physical activity.Artigo Científico Acesso embargado Tendência temporal da Incidência de Hepatite B em Santa Catarina no período de 2008 a 2015(2017) Krahl, MateusAbstract: Introduction: Hepatitis B (HB) is a public health problem in Santa Catarina. Objective: To analyze the temporal trend of the incidence of HB in the State of Santa Catarina from 2008 to 2015. Methodology: Ecological study of time series from 12,030 records of the Information System of Notification Diseases (SINAN) available from DIVE. Incidence rates of HB per 100,000 inhabitants (general according to sex, gender by age group, Health Region) and proportions for the sources of infection were calculated. The time trend was estimated using the simple linear regression method. Results: The overall incidence rate was stationary in Santa Catarina. The incidence for both sexes showed an increasing trend with a reduction in younger age groups and a rise in rates in the population over 40 years. There was a predominance of HB in males throughout the study period. In most cases the source of infection was unknown or unfilled in the notification form. The sexual route is the main cause of contagion, followed by the vertical route, both tending to increase. The Carboniferous Health Region was the only one with a significant decrease in rates, while the Alto Vale do Itajaí and Planalto Norte evidenced a significant increase in the indices. The regions of the West follow with the highest incidences of the State. Discussion: The high incidence of HB can be partly justified by the improvement in the notification systems and the diagnostic methods as well as by the epidemiological profile characteristic of this disease in the State. Vaccination certainly contributed to reducing the trend of incidence in individuals under 20 years of age. However, the aging of the population and the prolongation of sexual life culminated in an increasing tendency of the rates in the elderly population of Santa Catarina. Conclusion: The epidemiological singularity of HB in the state of Santa Catarina requires a broad public policy and a progressive increase in the vaccination coverage of the population.Artigo Científico Acesso embargado Vitamina D (25-OH-D) e memória de curto prazo em participantes de um ambulatório da memória(2017) Trevisol, RafaelDementias are a public health problem in developing countries, evidence shows that dementias are preventable provide timely interventions in modifiable risk factors are done. Vitamin D is associated to many cognitive skills and is considered as a protective factor or even treatment of cognitive decline. Objective: To evaluate the association between blood levels of vitamin D (25-OH) and short-term memory represented by the memory section of the Montreal Cognitive Assessment test (Brazilian version) controlled by sociodemographic and health variables. Methods: Cross sectional study based on patients files with 50 years old or more, analysed trough. Poisson regression in a memory clinic from February 2015 to May 2017. Results: We studied 210 individuals with a mean age of 70.8±8.6 years old, mean vitamin D blood levels of 26.5± 9.5 ng/dL. The mean score in the MoCA test was 17.0±7.5 points and the mean memory score (0-5 points) was 1.3±1.0. In the final multivariate model, there was a positive independent association between short-term memory and vitamin D blood levels, schooling, age, female gender and hypertension. Conclusion: These findings indicate that 25-OH vitamin D blood levels are associate to short term memory and may be a prognostic or screening tool for cognitive decline and dementia.