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Artigo Científico Acesso fechado Prose palpebral congenita e as complicações do tratamento(1123-11) CAMARGO, Maria Antônia Vicente de, JUNIOR, Astor GrumannObjetivo: Analisar as complicações do tratamento da ptose palpebral congênita atendidos em hospital de referência estadual, no período de 2010 a 2022. Métodos: Estudo de coorte histórica, realizado no hospital público de referência da grande Florianópolis. A população do estudo incluiu pacientes submetidos ao tratamento cirúrgico de elevação frontal da ptose palpebral congênita, no período compreendido entre janeiro/2010 a dezembro/2022, com análise descritiva de características clínicas e epidemiológicas. Resultados: 54 pacientes constituíram a amostra, cuja maioria era do sexo masculino 75,9%, com média de idade de 5,5 (desvio padrão) anos. Em relação à lateralidade, 12 (22,2%) pacientes apresentaram ptose apenas no olho direito, 20 (37%) apenas no olho esquerdo e 22 (40,7%) em ambos os olhos. Lagoftalmo foi a principal complicação observada, sendo que 35 pacientes (64,81%) apresentaram complicações transitórias e 19 (35,19%) com complicações definitivas. Conclusão: A avaliação da ocorrência de complicações no tratamento cirúrgico, a necessidade de reintervenção cirúrgica e as complicações do tratamento em relação ao tempo de pós-operatório são aspectos cruciais para melhorar os resultados clínicos e a segurança dos pacientes.Artigo Científico Acesso embargado A relação do tabagismo e do consumo de álcool com a gravidades das lesões coronarianas em pacientes com IAM(2017) Albuquerque, Luis GustavoBackground: Smoking is the most important risk factor for coronary heart disease (CHD) and ischemic events; alcohol consumption, on the other hand, appears to have a protective role. Objective: Assess the association between smoking and alcohol consumption with the severity of coronary artery injuries in patients with Acute Myocardial Infarction (AMI). Methods: Cross-sectional study, performed in public hospitals in the Florianopolis’ metropolitan area with 226 patients presenting at the emergency room with AMI from August 2016 to June 2017. Results: There was a difference in sex distribution, showing that 59.7% of men and 85.4% of women weren’t alcoholic (p<0.001). There was a higher prevalence of non-hypertensive patients who consumed alcohol than hypertensive ones (40.7% vs. 24.4% and p = 0.010) and patients without diabetes who had drinking habits than those diabetic (36.4% vs. 12.0% and p = 0.001). There was also a higher prevalence of non-diabetic patients who smoked than diabetic ones (38.1% vs. 22.0% and p = 0.035). A weak and negative correlation was found between the number of cigarettes per day and the pack-year with the TIMI frame count (r=-0.174 and p=0.041 and r=-0.192 and p=0.027, respectively). The other associations didn’t show statistical significance. Conclusion: The study showed that the number of cigarettes consumed per day and the pack-year is related to a smaller TIMI frame count, i.e., to a better coronary flow, which may be related to the Smoker’s Paradox. There was no correlation between the beverage type and quantity with the Syntax score, Ejection fraction and TIMI frame count.Monografia Acesso fechado Associação entre via de parto e resultados perinatais em gestantes de alto risco(2017) Puel, Ana Gabriela de OliveraIntrodução: A gestação de alto risco é aquela em que se verificam condições ou complicações que aumentam os riscos de desfecho materno e perinatal desfavoráveis, se comparadas à população geral. Tais condições estão mais associadas à indicação de cesariana – via de parto que geralmente apresenta piores resultados para o binômio mãe-filho. A correta indicação pode sim trazer benefícios. Porém, observa-se uma epidemia de indicações de parto operatório, principalmente no sistema privado. Objetivos: Avaliar a associação entre via de parto e resultados maternos e perinatais nas gestantes consideradas de alto risco obstétrico. Método: Estudo transversal que avaliou todas as gestantes classificadas como alto risco, que tiveram seus partos realizados na maternidade do Hospital Universitário Polydoro Ernani de São Thiago, e seus recém-nascidos, entre janeiro de 2010 e dezembro de 2014. A coleta foi realizada a partir de uma base de dados, e a diferença da prevalência nas variáveis independentes foram investigadas e testadas utilizando o teste do “Qui-quadrado”. Foram calculadas as Odds Ratios de acordo com as variáveis independentes associadas à via de parto. Resultados: A cesariana se apresentou como fator de risco para as seguintes variáveis: baixo peso ao nascer [OR=1,75 IC95%(1,37-2,21)], prematuridade [OR=1,73 IC95%(1,38-2,17)] e Ápgar de 1º minuto <7 [OR=1,35 IC95%(1,01-1,81)]. As complicações maternas não apresentaram relevância estatística no estudo utilizado. Conclusão: Os piores desfechos neonatais estiveram mais associados à cesariana, se comparados ao parto normal. Sendo assim, o uso exaustivo das tecnologias obstétricas pode trazer repercussões imediatas e futuras aos recém-nascidos.Monografia Acesso fechado Análise da influência do genótipo na carga viral dos pacientes infectados com o vírus da Hepatite C em um estado do Sul do Brasil(2017) Borges, Kleiton RosaIntroduction: Hepatitis C is a transmissible infectious viral disease, which manifests itself acutely, chronic and fulminant. Studies have shown that viral load decreases in 99% of patients in the fourth week of treatment, however, there are genotypes that are more resistant to treatment. These may be associated with a higher viral load. Based on the above, the present study aimed to analyze the influence of genotype on the viral load of patients infected with hepatitis C virus (HCV) in the State of Santa Catarina. Method: A cross-sectional study consisting of laboratory data from 856 patients infected with HCV, attended at the Central Public Health Laboratory of Santa Catarina, in the year 2015. Data were analyzed by the SPSS program. The qualitative data were presented in absolute and relative frequency and the quantitative as mean and standard deviation. The association between variables was calculated using the Chi-square test or Fisher's Exact Test or Kruskal-Wallis test and Dunn's post hoc test, as appropriate. p <0.05 was considered statistically significant. Results: A total of 856 patients were evaluated, of which 64.4% were male. The mean age was 50.74 ± 11.41 years and the mean HCV viral load was 5.69 x106 ± 0.89x106 log/mL. The Health region where it was evidenced more prevalence was Greater Florianópolis (22.3%). The most prevalent genotype was 1. However, when the analysis is made considering the subtypes, the most prevalent was the 3 in 38.8% of the patients, followed by 1/1a in 36.9%. There was a statistically significant association between age and genotypes 1, 2 and 3 (p< 0.05). When comparing HCV RNA quantification results in relation to genotypes, we observed that the mean viral load is higher in genotype 2 when compared to genotypes 1 and 3 (p<0.05). Conclusions: HCV in chronic patients predominated in males, in the Greater Florianópolis Region. The most prevalent genotype in the State was 1. However, when the result is expanded considering each of the subtypes, the predominant genotype was 3. There was an association between the age group and genotypes 1, 2 and 3. Genotype 2 presented a higher and statistically significant viral load when compared to genotype 1 and 3.Monografia Acesso fechado Tendência de mortalidade por Infarto Agudo do Miocárdio em Santa Catarina no período de 1996 a 2014(2017) Morais, Pedro de Castro Martins deIntroduction: Acute Myocardial Infarction (AMI) is a public health problem in world and in the Brazil, with high morbidity and mortality rates observed. It is very important to follow the evolution of this pathology. Objective: To analyze a trend of mortality due to acute myocardial infarction (AMI) in Santa Catarina, from 1996 to 2014. Method: Ecological study of time series study, based on the Mortality Information System (MIS), made available by the Department of Informatics of SUS (DATASUS). Rates calculated from census and intercensity estimates of the Santa Catarina (SC) population according to the Brazilian Institute of Geography and Statistics (IBGE). Selected deaths by AMI, ICD-10, code I21, of the resident population in the state, according to gender, age group and macro-regions. Performed simple linear regression. The Research Ethics Committee of the Southern University of Santa Catarina approved this study. Results: There was a steady trend in overall mortality rates and by sex (p> 0.05). As male and female age groups present a decreasing tendency from 30 years of age (p<0.05). Age groups older than 70 years presented the highest mortality rates. The South macro-region presents an increasing trend (r = 0.57, β = 0.749, p = 0.011). As macroregions of Greater Florianópolis and Great West present a decreasing trend (p<0.05). Conclusion: The rates of general mortality and sex in Santa Catarina are stationary. The age groups above 30 years in both sexes are descendants. An increasing and significant trend in the South macro-region.Monografia Acesso fechado Correlação da perfusão coronariana pós-angioplastia primária com a função ventricular pós-infarto(2017) Bald, Ana PaulaBackground: Acute Myocardial Infarction (AMI) stands out for its high prevalence. Primary angioplasty is the most effective treatment, in addition to allowing the analysis of coronary perfusion by TIMI frame count (TFC). The severity of AMI is related to worse prognosis and development of left ventricular dysfunction. Objectives: To correlate coronary perfusion after primary angioplasty with post-infarction ventricular function; to describe the demographic characteristics, comorbidities, life habits and family history of the study population; to correlate perfusion after primary angioplasty, post-infarction ventricular function and SYNTAX score (SXs) with each other and with symptom-to-door time, door-to-reperfusion therapy time and total ischemic time; to associate comorbidities, life habits, family history and involvement of the anterior wall with coronary perfusion after primary angioplasty. Method: A cross-sectional study including 55 patients admitted in Santa Catarina’s Institute of Cardiology with diagnosis of AMI with ST-segment elevation, from August to November, 2016. Data collection from interview and consultation in medical records. Analysis by SPSS 13.0, Chi-square test, Student t and p≤0.05. Results: 63.3% were males, mean age 58.39 years. Arterial hypertension (63.3%), family history (47.3%) and dyslipidemia (36.4%) were the most prevalent clinical variables. There was no significant correlation between TFC and left ventricular ejection fraction (LVEF). There was a correlation between TFC and SXs (r=0.31, p=0.041), in addition to a non-significant correlation between SXs and LVEF (r=0.31, p=0.051) and between symptom-to-door time and LVEF (r=0.31, p=0.058). Conclusion: Coronary perfusion is not correlated with post-infarction ventricular function, but SXs is positively correlated with coronary perfusion and has a non-significant correlation with post-AMI ventricular function and symptom-to-door time.Artigo Científico Acesso embargado Fatores associados ao insucesso no implante de lentes intraoculares tóricas na cirurgia de catarata(2017) Guilherme, GrasieleIntroduction: Surgical success depends on the exact biometry for calculating the power of the intraocular lens (IOL). Objective: To evaluate factors associated with failure to implant IOL. Methods: Case-control study including 182 eyes of 127 patients submitted to the Acrysof® IOL implant from January/2010 to December/2016. Patients with residual astigmatism > 0,75 diopters represent cases (47) and, astigmatism ≤ 0,75 diopters, controls (135). Pre- and post-operative data analysis was performed using the Student T- test for variables with normal distribution. The significance level established was p ≤ 0,05. Results: Failure was observed in 25,1% (47 cases). The mean age in the cases was 73.4 ±9.8 and controls was 69.7 ±11.8. When evaluating preoperative cylindrical refraction, we observed higher values related to failure, with a mean of -1,79 ±1,05 for cases and -1,31 ±0,90 for controls, p < 0,01 by Student's t-test. The total aberration (0.346 ± 0.258 in the cases and 0.196 ± 0.104 in the controls) and the proportion between anterior and posterior cornea curvature (83.39 ± 5.17 and 82.35 ± 2.00) were higher in the cases. As for total corneal astigmatism, cases had higher values, being -3.06 ± 1.79 for cases and -1.73 ± 1.20 for controls, respectively. A significant difference between the K1 modulus obtained by Pentacam® and K1 TCRP (p <0.01) was noted. Conclusions: Despite the low rates of residual astigmatism, a better understanding of the factors associated with failure becomes useful, this study showed significant variables that could be related to surgical failure, suggesting that the TCRP, relationship between anterior and posterior curvature, total corneal astigmatism, are factors to be explored, showing the importance of the posterior cornea in the calculation of IOL power.Artigo Científico Acesso embargado Infecções em próteses ortopédicas: avaliação dos fatores associados no hospital Governador Celso Ramos(2017) Henrique Junior, Edson AcioliIntroduction: The number of procedures of arthroplasty has been increasing significantly over the years and consequently its complications such as periprosthetic joint infection. Objective: To evaluate the factors associated with periprosthetic joint infection in the Hospital Governador Celso Ramos, analyzing the clinical and demographic characteristics and the factors related to the surgical procedure. Methods: Observational case control study. 233 patients were selected, 184 controls (without infection) and 49 cases (with infection). The study was carried out from the collection of data in medical records with a tool prepared by the authors. Results: Among the clinical characteristics evaluated, males were more present in the group that evolved with infection, showing statistical significance (OR = 2.070, p = 0.019). In the variables related to the surgical procedure, patients who had already performed arthroplasty had a higher chance of infection (OR 1.812, p = 0.047). When the reason of the procedure was the revision of the prosthesis, this variable presented statistical significance (OR = 3.309, p = 0.001). The main reason the patients underwent arthroplasty was osteoarthritis, and 79% of the prosthesis were in the hip. Discussion: It was observed that factors associated with the outcome were the presence of the male gender and when the reason for the procedure is due to the necessity of revision of the prosthesis. The other variables analyzed in the study probably did not present correlation due to the reduced number of medical records analyzed. Conclusion: It is up to the professionals in the area to step in on the modifiable risk factors to avoid an increase in morbidity and mortality and consequently in costs.Artigo Científico Acesso embargado Tempo de diagnóstico histopatológico e fatores associados de pacientes com lesões compatíveis com melanoma triados pela teledermatologia(2017) Grolli, CarolinaFOUNDATIONS: Melanoma corresponds to the most severe type of skin cancer and teledermatology may represent an attempt to serve populations with low density of specialists, including for the diagnosis and management of patients with suspected lesions. OBJECTIVE: To analyze the outcomes and referrals of patients screened by teledermatology with suspicion of melanoma. METHODS: Retrospective Cohort study developed through the census reports of teledermatology from January to December 2014, at the Telehealth Nucleus- Santa Catarina. The patients were contacted to elucidate the possible outcomes of each case. RESULTS: 220 reports were analyzed, 69 patients participated in the study. Most were referred via TFD and approximately 24% lost follow-up. More than half performed surgery and there was a homogeneous distribution between histopathological results for melanoma and non-melanoma lesions. In the Extremo Oeste region of the state there was a longer average time to perform dermatological consultation and to perform surgery, relative risk of 5 and 8 times respectively (p <0.05). There was no statistical significance when compared to referrals. LIMITATIONS OF THE STUDY: Analysis of a short period of time and the population exclusively from Santa Catarina may not be representative for other populations in the country. CONCLUSIONS: Further studies should be performed to investigate the loss of follow-up of patients with suspected melanoma, screened by teledermatology as well as to analyze the Extremo Oeste discrepancy in the management of these patients.Artigo Científico Acesso embargado Tendência temporal da incidência de tuberculose no estado de Santa Catarina no período de 2001 a 2015(2017) Abreu, Rafaela Fujii deThe objective of this study was to analyze the temporal trend of Tuberculosis (TB) incidence in the State of Santa Catarina from 2001 to 2015. Ecological study of time series of TB incidence trends, selected from the Aging Information System Notification (SINAN) of the Ministry of Health in the resident population in the State, by sex, age group and macro-regions. Simple linear regression was performed. Approved by the Research Ethics Committee of the Southern University of Santa Catarina. Stable trend in TB rates in the state. There is a strong correlation with significance in males, with an increase of 0.465/100.000 in the rate per year. The male age groups from 0 to 19 and 20 to 29 years presented an increase in rates per year of 0.159/100.000 and 0.606/100.000 respectively. The male age range from 40 to 49 years old presented a reduction of the rates of 1.292/100.000, as well as the female rate of 20 to 29 years, of 0.802/100.000. In the Mid-Western regions (β = -0.381, p= 0.05), the Itajaí River Mouth (β = -2,158, p= <0.001) and the North Plateau (β = -0.621, p=0.006) (β= 0.968, p= 0.009) and South (β = 0.631, p= 0.001). The incidence rates of TB in Santa Catarina are stationary. Growing trend in males, in the age groups up to 29 years and decreasing in males between 40 and 49 years and females 20 to 29 years. Macroregions in the coastal belt are growing. The macroregions located in the Center West of the state downward trend.Artigo Científico Acesso embargado Fatores associados aos sintomas de doenças atópicas em crianças de 6-7 anos em um município da região Sul do Brasil(2017) Kozelinski, Julia CarvalhoIntroduction: The Atopic diseases are a important world prevalence syndrome that increased in its incidence and severity. The risk factors associated to the diseases include the interaction between genetics and ambiental factors. Objetive: Analyse the factors associated to the symptoms of atopic diseases in children from 6 to 7 years in Palhoça city - Santa Catarina. Methods: Observational study case-controled nested to a retrospective cohort wich evaluated 6-7 years children in Palhoça - Santa Catarina. The questionnaires were applied to the children’s mothers and the symptoms of atopic diseases were screened through the Internacional Study of Asthma and Allergy in Childhood (ISAAC) questionaries. Results: A total of 255 children participated the study (85 cases and 170 controls). The risk factors significantly associated to the atopic diseases were: family history of asthma (OR: 4,61; IC 95%: 0,73-2,63), rhinitis (OR: 3,46; IC 95%: 1,90-3,26) and atopic eczema (OR:3,42; IC95%: 1,91-6,14).). Mother’s gestacional history of infections as vaginal discharge (OR = 4,25; IC 95% 2,31-7,84). Smoking at home (OR: 2,00; IC 95%: 1,10-3,64) and maternal smoking (OR: 1,39; IC 95%:0,67-2,91). Mold/moisture in the bedroom (OR: 3,34; IC: 95%: 1,82-6,12) and pets at home (OR: 1,77; IC 95%: 1,04-3,02). Conclusion: atopy cases are associated with family history, maternal and neonatal infections, and environmental exposures such as tobacco smoking and mold.Artigo Científico Acesso embargado Fatores de risco associado a sobrepeso e obesidade em crianças de 5 a 12 anos do município de Palhoça- SC(2017) Grezzana, Celyna ScariotABSTRACT Objective: Characterizing the factors associated with overweight and obesity in children aged 5 to 12 years old from the city of Palhoça - Santa Catarina state. Methods: A case-control epidemiological study was carried out to analyze the medical records of children aged 5 to 12 years old assisted at the Municipal Policlínica of Palhoça from 2013 to 2016. 191 children diagnosed with overweight or obesity according to the WHO´s age curves of BMI (Z score > or = 1) and 409 children with adequate weight for their age and height (Z score < 1) were selected. The univariated analysis and after multivariate regression to evaluate the covariables without confounding factor. Results: The risk of overweight and obesity in the sociodemographic and behavioral variables was identified in the study. At the multivariated regression it was found meaningfulness between screen time (OR = 2.60), parents' level of schooling (OR = 3.42), exclusive breastfeeding for at least 4 months (OR = 2.52), introduction of whole cow's milk before 12 months old (OR = 2.75) and current hypercaloric diet (OR = 6.73). Protective factors against overweight and obesity were children who had prenatal intrauterine growth restriction (IGR with OR = 0.23) and children who were born small for gestational age (SFGA with OR = 0.38). Cesarean child-birth was a risk factor for overweight or obesity (OR = 1.69). Conclusion: The main risk factors associated with overweight and obesity in children aged 5 to 12 years-old in the city of Palhoça - SC were parents' level of schooling, cesarean child-birth, eating habits from birth, as well as sedentary behavior and excessive time in front of screen. These factors are modifiable for the prevention of overweight and obesity.Artigo Científico Acesso embargado Infiltração por linfócitos T CD8+ e sua relação com a graduação tumoral em neoplasias primárias do sistema nervoso central(2017) Laitart, AlessandraObjetivos O conhecimento sobre o microambiente tumoral e a interação neoplásica com as células inflamatórias permanece pouco elucidado, apesar dos recentes estudos sobre imunoterapias no tratamento de neoplasias primárias. Neste estudo, investigamos a existência da associação entre a resposta linfocitária e a atividade proliferativa em neoplasias primárias do SNC. Também foi investigada a relação entre a concentração linfocitária tecidual entre as diferentes categorias da classificação da OMS. Métodos Foram avaliados 80 casos classificados como neoplasias primárias do SNC, oriundos de centro de referência e diagnosticados entre 2011 e 2015. Foram obtidas as concentrações teciduais de TILs CD45+, CD8+ e CD20+ e os marcadores de atividade proliferativa foram estimados pelo marcador Mib-1 (Ki67) e pela atividade mitótica. A densidade vascular e graduação tumoral também foram analisadas. Resultados Não foi encontrada associação entre os marcadores de proliferação e a concentração de TILs CD45+, CD20+ e CD8+. Foram observadas distintas concentrações de TILs CD8+ entre os tumores dos graus I e III, sendo menor nos tumores de alto grau. Houve uma maior concentração vascular em graus tumorais elevados. Não foram observadas diferenças entre TILs CD45+ e CD20+ nas diferentes categorias da classificação da OMS. Conclusão Neste estudo foi encontrada uma diferença significativa entre a concentração de TCD8+ nas categorias da classificação da OMS. Embora a relevância clínica deste achado permaneça obscura, evidências científicas atuais sugerem estreitas relações entre o sistema imune e tumores primários do SNC; entretanto, novos estudos serão necessários para elucidação dos mecanismos subjacentes e inferências sobre implicações prognósticas e terapêuticas.Artigo Científico Acesso embargado Preferência por comportamentos favoráveis à prática de atividade física em crianças com sintomas de asma e/ou rinite(2017) Piovezan, Aline de Azevedo; Traebert, JeffersonBoth asthma and rhinitis seems to influence children’s lives in many different ways, including impairment of physical activity level. This paper aimed to analyse preferences for behavior conducive to physical activity and physical activity levels in children with symptoms of asthma and/or rhinitis in children aged 6-7 years in a city of Southern Brazil. A cross-sectional study was performed that evaluated the presence of symptoms of asthma and rhinitis through ISAAC questionnaire and its association with behavior conducive to physical activity and with physical activity levels that were evaluated with the Netherlands Physical Activity Questionnaire (NPAQ). The Student’s t test was used to assess if independent variables were associated to behavior conducive to physical activity and physical activity levels. ANOVA oneway followed by Tukey’s post hoc test were used to compare behavior conducive to physical activity and physical activity levels among groups. No relationship between the level of physical activities and asthma and rhinitis symptoms was detected among the participants. Children with asthma symptoms showed a weaker preference for drawing, painting or reading magazines.Artigo Científico Acesso embargado Tendência de mortalidade por câncer de pulmão na região Sul do Brasil, no período de 1996 a 2015(2017) Inoue, Aline CruzObjective: To analyze the Mortality Trend for lung cancer in the southern region of Brazil from 1996 to 2015. Methods: Ecological study of temporal trends, carried out with data from the Mortality Information System (SIM) of the population of southern Brazil , who used the 10th revision, CID-10 code C34. Simple linear regression was performed. This study was approved by the Research Ethics Committee of the Southern University of Santa Catarina. Results: 95,340 deaths were analyzed. There was a strong upward trend in mortality rates in the Southern Region with annual percentage change of 2,78%. In the states of the region, the variation was 3,41% in Santa Catarina, 3,42% in Paraná and 2,44% in Rio Grande do Sul. The male gender presented variation of 2,01%, and the female sex 4,48% per year. In the male age groups there was a downward trend of -3.04% per year in the population aged 40 to 49 years and of -0,19% in the population aged 60 to 69 years. Already in the population of 80 years or more it was observed a strong tendency increasing with 4,31% in the rate per year. In the female sex, there was an increasing tendency in the age groups above 40 years, with a greater percentage variation in 80 years or more (4,31%). Conclusions: There is an upward trend in lung cancer mortality rates in the South Region and states in both sexes and age groups over 40 years in women and 80 years in men. The age groups 40-49 and 60-69 years show a decreasing trend.Artigo Científico Acesso embargado Evolução temporal da prevalência de resistência da Escherichia coli aos antibióticos nas infecções comunitárias do trato urinário(2017) Mattos, Eduarda LencinaObjective: To determine the temporal evolution of resistance of Escherichia coli to antibiotics. Methods: Study of the temporal trend of bacterial resistance to antibiotics in outpatients with urinary tract infections from a single laboratory database between 2004 and 2013. We studied 61,264 protocols that met the inclusion criteria. The protocols were divided by age, sex and bacterium identified. The time trend was performed for and stratified by antibiotic. Results: 90.6% of the patients were female. Escherichia coli was the most prevalent uropathogen in both sexes, followed by Klebsiella pneumoniae. Staphylococcus saprophyticus was detected more frequently in females aged 15 to 59 years. The highest prevalence of Proteus mirabilis occurreds in males aged 0 to 9. Escherichia coli showed an upward trend of resistance (p < 0.05) for nalidixic acid, ampicillin, cephalothin, cefuroxime, ciprofloxacin, gentamicin, nitrofurantoin and norfloxacin. Conclusions: The constant capacity of bacterial adaptation makes antibiotic resistance inevitable and irreversible. Thus, to reduce this bacterial adeptness, specific empirical therapies for each region and the reduction of inappropriate use of antimicrobials become essential measures.Monografia Acesso fechado Prevalência e os fatores associados aos tipos de violência na gestação(2017) Gonçalves, Camila Maiara FrancoIntroduction: Violence against women is any act that could result in physical, sexual or psychological harm to the victim. It has a multifactorial origin and brings countless consequences, especially if it occurs during pregnancy. Objective: To understand the prevalence and factors associated with the types of violence during pregnancy. Method: A cross-sectional study was carried out with 412 women residing in the state of Santa Catarina, who were victims of violence during pregnancy, reported in the SINAN database in 2014. Data were analyzed in SPSS 18.0, using the Chi-square test and Prevalence Ratio with Confidence Interval 95% (p <0.05). Approved by CEP-UNISUL. Results: There was a higher prevalence of violence in white women (75.5%), aged 11 to 15 years (24.8%), with low education (82.2%) and in the third trimester of pregnancy (39.6%). The main offender was the spouse (22.1%) and physical aggression was the most common (50.7%). Associations (p <0.05) were found between physical violence and age, schooling, gestational age and spouse as offender. Psychological violence (p <0.05) was associated with the onset of pregnancy and the offender (ex-partners). In sexual violence, age, gestational age and offenders (father, boyfriend, acquaintances and unknown people) were associated (p <0.05). Conclusion: Social, demographic and gestational age aspects are related to the practice of physical, psychological and sexual violence in pregnant women.Artigo Científico Acesso embargado Imagem corporal a longo prazo de orquiectomia subcapsular comparada a total com epididimoplastia(2017) Silva, Eduardo ViníciusINTRODUCTION: Castration is part of the treatment of metastatic prostate cancer. Surgical castration has some advantages over pharmacological castration. The subcapsular bilateral orchiectomy technique is the most used, but it has a significant impact on the body image of these patients OBJECTIVE: To evaluate outcomes related to body image at 1 year of patients submitted to surgical castration using subcapsular technique compared with total orchiectomy with preservation of the epididymis and epididymoplasty. METHODS: A randomized clinical trial with 106 patients with metastatic prostate cancer randomized by simple draw and allocated to two groups. The testicular volume was measured with an orchidometer. The Brazilian version of the Body Appreciation Scale (BAS) questionnaire for the elderly was applied to evaluate body image after 1 year. RESULTS: A total of 62 patients (58.5%) underwent simple subcapsular orchiectomy and 44 (41.5%) underwent total orchiectomy with epididymoplasty. There was no difference between castration levels. Even with a bigger median volume of the pseudo neo-testis after 1 year (12 versus 6.5 mL, p <0.01), the patients submitted to epididymoplasty report no significant difference regarding satisfaction with castration method as well as with scores of the BAS questionnaire for the elderly of body image. CONCLUSION: There is better preservation of the scrotal volume in the long term in patients submitted to epididymoplasty. However, this objective data does not improve body image in this population.Monografia Acesso fechado Comparação da prevalência de comorbidades em pacientes com Arterite de Takayasu e Arterite de células gigantes(2017) Ferreira, Cristiane JansonIntroduction: Vasculitis are associated with high morbi-mortality caused by cardiovascular disease, through accelerated atherosclerosis. This process has a multifactorial risk factors, which could be related to aspects of the inflammatory disease itself, to the use of steroids and to the presence of traditional risk factors of cardiovascular diseases. Objective: Analyze if patients with large vessels vasculitis (LVV) have higher frequency of comorbidities and compare the prevalence between Takayasu arteritis (TAA) and giant cell arteritis (GCA). Method: 45 medical records of patients who had LVV were analyzed in a retrospective study in Florianopolis, Brazil. Demographic data were collected, as well as related to clinical tidings. These data were compared between the vasculitis groups (TAA and GCA) through analysis on SPSS 18.0, t-student test and chi-squared test or Fisher’s exact test, p ≤ 0,05. Project was approved by Human Research Ethics Committee of the related institutions. Results: Among the 45 patients, 22 had TAA and 23 had GCA. 84,4% of the patients were women. The percentage of systemic arterial hypertension, diabetes mellitus and dyslipidemia on TAA were 77,3%, 9,1% and 95,5%, respectively. In the same order these comorbidities were found in GCA patients in 87%, 39,1% and 100%. The control of dyslipidemia was not satisfactory in both groups. Lipid profile did not have a significant difference between TAA and GCA. Conclusion: Patients with GCA have higher prevalence of diabetes mellitus when compared to general population and to TAA. The higher prevalence of systemic arterial hypertension and dyslipidemia found in LVV combined with endothelial inflammation due to vasculitis can contribute to accelerate atherosclerosis and should be evaluated and well treated.Monografia Acesso fechado Fatores associados à gravidez e aos desfechos perinatais em casais adolescentes no estado de Santa Catarina(2017) Cabral, Thalyta Indja DittertIntroduction: Adolescence is a critical period of human development. The occurrence of pregnancy at this stage is related to risks to the mother and her newborn. Numerous studies are focused on the adolescent mother and her newborn, neglecting the importance of paternal age. This study addresses the risk factors for teenage pregnancy with a focus on the "adolescent father and mother" binomial. Objective: To investigate factors associated with pregnancy in adolescent couples and the perinatal outcomes. Method: A cross-sectional study with SINASC/SC data, totaling 17,156 deliveries of primiparous women with single pregnancy. Prevalence ratios adjusted according to hierarchical model and Percentage Attributable Risk (RAP) were calculated to obtain the excess in the chances of the outcomes among the adolescent couples. Results: Findings show that in the 16.6% of deliveries among adolescent mothers, more than 1/3 of these occurred among live births of adolescent parents. This group had a less privileged profile regarding socio-demographic factors, prenatal care and an excess in the relative risk and attributable risk for practically all the variables of interest when compared to pairs of adolescent mother and adult father. Conclusion: When strategies are designed directed at the issue of adolescent pregnancy, it is essential to look at the adolescent couple as a special group, and the adolescent father as an independent factor, with an important role in the final definition of risk in this group.